eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | acanthosis nigricans |
| Comorbidity | C0011847|diabetes |
| Sentences | 5 |
| PubMedID- 26051063 | acanthosis nigricans has been associated with type 2 diabetes mellitus, obesity, endocrinopathies, drugs, and malignancies. |
| PubMedID- 22028737 | Frequent signs of acromegaly include enlarged acral features, soft tissue edema, perspiration, jaw underbite, skin tags, and acanthosis nigricans associated with diabetes mellitus. |
| PubMedID- 21992016 | Defects in insr are the cause of insulin-resistant diabetes mellitus with acanthosis nigricans type a (iran type a, mim:610549), a syndrome characterized by the association of severe insulin resistance manifested by marked hyperinsulinemia and a failure to respond to exogenous insulin with the skin lesion acanthosis nigricans and overian hyperandrogenism in adolescent female patients. |
| PubMedID- 20339196 | She showed diabetes mellitus with severe acanthosis nigricans and hyperinsulinemia without obesity. |
| PubMedID- 23263437 | This disorder is characterized by insulin-resistant diabetes mellitus, hyperinsulinemia, deficiency of subcutaneous fat, acanthosis nigrican, growth retardation, coarse and senile appearance, precocious puberty, and dental prematurity, enlarged genitalia, and pineal hyperplasia. |
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