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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease c syndrome
Comorbidity |obesity
Sentences 307
PubMedID- 25815341 Visceral obesity, the central core of metabolic syndrome (mets), is conceived as the pathogenic basis of an increased cardiovascular burden and is related with changes in cytokines.
PubMedID- 22582147 Since in both vertebrates and in invertebrates δ9 desaturases has key function in cellular lipid partitioning and homeostasis it may be a potential target for therapeutic intervention to control obesity and other aspects of metabolic syndrome (dobrzyn and ntambi 2005).
PubMedID- 26558034 The latter must be viewed as a novel renal manifestation of insulin resistance in the context of metabolic syndrome with central obesity as its primary key feature.
PubMedID- 21711426 Increasing age, obesity and the presence of multiple features of metabolic syndrome, especially diabetes, are associated with a higher probability of having non-alcoholic steatohepatitis (nash).
PubMedID- 20883237 In the population with abdominal obesity and components of the metabolic syndrome, telmisartan did not increase insulin sensitivity.
PubMedID- 24396679 The crucial components that may link abdominal obesity to other features of the metabolic syndrome and end-organ damage are presumably the presence of insulin resistance and elevated insulin levels, increased inflammation with macrophage infiltration in fat tissues with concomitant release of proinflammatory cytokines, and endothelial dysfunction, which all may lead to sht.
PubMedID- 21668294 Whereas fatness alone endangers physiological performance of even simple tasks, the associated co-morbidity of obesity including metabolic syndrome in all its manifestations is a far more critical problem.

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