eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | metabolic syndrome x |
| Comorbidity | |obesity |
| Sentences | 300 |
| PubMedID- 22303936 | How obesity causes symptoms of metabolic syndrome, in particular cardiomyopathies, is still largely unknown. |
| PubMedID- 23903497 | Results: multiple logistic regression analysis revealed that visceral obesity was independently associated with metabolic syndrome, platelet count, high-density lipoprotein level, and serum viral load in elderly patients (>/=65 years). |
| PubMedID- 25172520 | obesity with and without metabolic syndrome: do vitamin d and thyroid autoimmunity have a role. |
| PubMedID- 25875119 | A green algae mixture of scenedesmus and schroederiella attenuates obesity-linked metabolic syndrome in rats. |
| PubMedID- 26255568 | metabolic syndrome, abdominal obesity and hyperuricemia in schizophrenia: results from the face-sz cohort. |
| PubMedID- 21964613 | obesity is associated with the metabolic syndrome--a pathophysiologically distinct inflammatory process comprised of central obesity, insulin resistance, hypertension, and atherogenic dyslipidemia. |
| PubMedID- 25013207 | obesity is the hallmark of the metabolic syndrome that represents a cluster of different disorders which predispose people for the development of chronic metabolic diseases including t2dm and cardiovascular diseases [34]. |
| PubMedID- 22567052 | obesity, an integral component of the metabolic syndrome and type 2 diabetes, predisposes to the toxic effects of fatty acids on the myocardium and the additional detrimental effects of cytokines and angiotensin ii released by adipose tissue. |
| PubMedID- 21083873 | Our patient's medical history included metabolic syndrome with second-degree obesity as indicated by a body mass index of 39 kg/m2, orally treated diabetes mellitus type 2b, stage ii arterial hypertension according to world health organization (who) criteria, compensated renal insufficiency following a left nephrectomy for a hypernephroid clear-cell carcinoma (p-t2n0m0g1) in 1985 and an uncertain penicillin allergy, although piperacillin was tolerated with no problems during the reported treatment. |
| PubMedID- 20883237 | In the population with abdominal obesity and components of the metabolic syndrome, telmisartan did not increase insulin sensitivity. |
| PubMedID- 20490316 | This corticosterone index could be correlated with an increase in both obesity and symptoms of metabolic syndrome [43]. |
| PubMedID- 25961053 | In contrast to the zdf male, the male zdsd rat maintains a moderately long period (approximately eight weeks) of prediabetic metabolic syndrome with obesity, followed by progression to overt diabetes and its complications. |
| PubMedID- 23689359 | obesity is often part of the metabolic syndrome, a condition which includes insulin resistance, dyslipidemian, reduced hdl cholesterol, and hypertension. |
| PubMedID- 25436720 | obesity also is associated with metabolic syndrome, which is a risk factor for breast cancer. |
| PubMedID- 25527815 | Background: obesity is the hallmark of the metabolic syndrome representing a major global health problem. |
| PubMedID- 25404888 | The metabolic syndrome is typically associated with abdominal obesity and comprises disturbances in glucose and/or lipid metabolism and/or hypertension. |
| PubMedID- 24617029 | obesity with no metabolic syndrome and adipose tissue expansion based solely on risk factors and inflammatory marker of coronary heart disease in premenopausal women. |
| PubMedID- 20436743 | Diabetes, hypertension, metabolic syndrome, smoking, obesity, etc) remain similar to those described elsewhere in the world. |
| PubMedID- 22043170 | Despite its rarity, there is considerable interest in understanding the molecular basis and biochemical pathways of alström syndrome as a monogenic model for metabolic syndrome with obesity, insulin resistance, diabetes mellitus, hypertriglyceridemia and hypertension as common features. |
| PubMedID- 20981493 | Lower testosterone levels were associated with central obesity- a strong component of a metabolic syndrome, and unsubstituted testosterone deficiency might be an important cardiovascular risk factor in patients with hypopituitarism. |
| PubMedID- 20061420 | obesity without established comorbidities of the metabolic syndrome is associated with a proinflammatory and prothrombotic state, even before the onset of puberty in children. |
| PubMedID- 22333076 | [epidemiological study on the association between obesity with metabolic syndrome in obese children and adolescents of nanning city, guangxi]. |
| PubMedID- 21383912 | Both factors are associated with obesity and a range of metabolic syndromes (figure 3). |
| PubMedID- 21799635 | The key risk factors that need to be controlled in the perimenopausal woman are hypertension, dyslipidemia, obesity, and other components of the metabolic syndrome, with the careful control of diabetes. |
| PubMedID- 22277141 | While obesity is associated with the metabolic syndrome, some obese individuals do not possess the constellation of the metabolic abnormalities and are referred to as metabolically healthy but obese (mho) persons. |
| PubMedID- 26298466 | Thbs1 may act as a critical circulating factor that couples obesity with metabolic syndrome and diabetes in humans. |
| PubMedID- 24130367 | Hence, excess mortality in type 2 diabetes has also been attributed to traditional risk factors, such as obesity and other components of the metabolic syndrome (6,7), and to socioeconomic factors (8). |
| PubMedID- 22778575 | The patient had metabolic syndrome with obesity, a history of hypertension for 10 years, diabetes mellitus type ii. |
| PubMedID- 26400710 | Glycyrrhizin, a major constituent of licorice (glycyrrhiza glabra) root, has been reported to ameliorate insulin resistance, hyperglycemia, dyslipidemia, and obesity in rats with metabolic syndrome. |
| PubMedID- 20927114 | Therefore, we focused on the spontaneously hypertensive corpulent rat (shr/n-cp), a model with type 2 diabetes, obesity and features of the metabolic syndrome to characterize retinal changes at a structural and functional level. |
| PubMedID- 22809366 | In addition, fatty liver is a manifestation of metabolic syndrome, and is associated with obesity, type 2 diabetes mellitus (t2dm), and hypertriglyceridemia [11]. |
| PubMedID- 23223931 | It is epidemiologically established that obesity is frequently associated with the metabolic syndrome and poses an increased risk for the development of type 2 diabetes mellitus and cardiovascular disease. |
| PubMedID- 24602590 | Results from baseline heart health screenings identified high obesity rates, high prevalence of metabolic syndrome, and low fruit and vegetable consumption as priority risk factors to address (16). |
| PubMedID- 22905200 | The specific questions we set out to address in this report were: (1) what are the major gut microbial subpopulations in this population and how does their distribution vary in obesity and with metabolic syndrome phenotypes? |
| PubMedID- 22723994 | Some hypothesized that sua mediates obesity and other features of metabolic syndrome by reducing endothelial nitric oxide and decreasing insulin-mediated glucose uptake in skeletal muscle [8]. |
| PubMedID- 26110103 | obesity is closely associated with metabolic syndrome, type 2 diabetes mellitus (t2dm) and cardiovascular diseases. |
| PubMedID- 25861160 | In animal models, oa-no2 has demonstrated benefits in hypertension [11], vascular neointimal proliferation [12], obesity with the metabolic syndrome [13], and hyperglycemia in diabetes [14]. |
| PubMedID- 21270259 | Thus, available information suggests that obesity and other facets of metabolic syndrome involve deregulation of signaling pathways mediated by ppar. |
| PubMedID- 24567686 | As metabolic syndrome correlates directly with obesity andsedentary lifestyles, health education for patients is of significant importance in theself-management of risk factors, such as obesity, high blood pressure, and smoking10). |
| PubMedID- 20836727 | These patients share common features like obesity with metabolic syndrome. |
| PubMedID- 20302640 | In addition, cerebellar degeneration can be caused by systemic diseases such as diabetes mellitus [74], chronic alcoholism [75], or obesity with metabolic syndrome [45,46]. |
| PubMedID- 25919692 | obesity complicated by the metabolic syndrome and type 2 diabetes mellitus are commonly comorbid conditions[2]. |
| PubMedID- 23465506 | Background: asthma has been linked to obesity and the presence of the metabolic syndrome. |
| PubMedID- 22847239 | obesity is the hallmark of the metabolic syndrome and predisposes patients to the development of major chronic metabolic diseases including type 2 diabetes mellitus. |
| PubMedID- 22509382 | A possible role for the gut microbiota in obesity and additional aspects of the metabolic syndrome was recently proposed [59]. |
| PubMedID- 23921778 | Conclusions: individuals with obesity and components of the metabolic syndrome reported significant improvements in most domains of the quality of life with a modest weight loss of 3.7% of initial weight, which was achieved within the first 6 months of treatment. |
| PubMedID- 22768054 | Wistar ottawa karlsburg rt1u (wokw) rats are white in color (albino), powerfully built and develop facets of metabolic syndrome with obesity, dyslipidemia, insulin resistance, hyperinsulinemia, hyperleptinemia and glucose intolerance [5]–[10]. |
| PubMedID- 20230058 | When ep was given at low, medium, and high dosages (94, 188, and 470 mg/kg) to sucrose water-treated wistar rats for four weeks, alleviation of symptoms associated with metabolic syndrome, including obesity, insulin resistance, hypertriglyceridemia, and hypertension, accompanied by hepatic acc inactivation, was seen in the low dosage group. |
| PubMedID- 22555437 | Conversely, 11β-hsd1 overexpression in adipose tissue completely recapitulates the metabolic syndrome with obesity, insulin resistance, hypertension, and dyslipidemia. |
| PubMedID- 24064364 | Epidemiological data indicate that an adverse maternal environment during pregnancy predisposes offspring to metabolic syndrome with increased obesity, and type 2 diabetes. |