eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | non-alcoholic fatty liver disease |
| Comorbidity | |obesity |
| Sentences | 164 |
| PubMedID- 21810560 | Many genes encoding mitochondrial proteins in skeletal muscle and fat are negatively correlated with body mass [8,24,25] nafld is commonly associated with obesity and insulin resistance; both conditions are characterized by decreased oxygen consumption, atp production, and reduced content of respiratory proteins in the fat, muscle and liver [8]. |
| PubMedID- 24748893 | Childhood obesity may lead to nafld in every age group. |
| PubMedID- 24232498 | Mice fed an i3o-supplemented hfd also showed a decrease in non-alcoholic fatty liver, a condition associated with obesity in which deposits of fat cause the liver to become enlarged and exhibit a milky pale color, showing evidence of lipid accumulation (figure 3c). |
| PubMedID- 21278140 | nafld is closely associated with abdominal obesity (14). |
| PubMedID- 22966224 | Hepatic steatosis without excessive alcohol intake, called nonalcoholic fatty liver disease (nafld), is commonly associated with obesity and insulin resistance [1, 2]. |
| PubMedID- 22194737 | The reported prevalence of obesity in patients with nafld varies from 30 to 100% [8] and increases with increasing bmi. |
| PubMedID- 20731535 | nafld is strongly associated with insulin resistance, obesity, hypertension, and dyslipidemia and is now regarded as the liver manifestation of the metabolic syndrome (3). |
| PubMedID- 22374640 | Fourth, obesity in nafld is associated with dysfunctional adipose tissue and lipotoxicity that promotes ir (19,21,27) and pancreatic β-cell dysfunction (28,29). |
| PubMedID- 26439744 | Since nafld is closely associated with obesity, insulin resistance and type 2 diabetes[11–13], it is suspected that adipose tissue and skeletal muscle may play an important role in the development of nafld. |
| PubMedID- 25993257 | In addition to cardiovascular comorbidities, obesity is also associated with non-alcoholic fatty liver disease (nafld), the hepatic expression of the ms [3]. |
| PubMedID- 26395497 | Similar patterns were inferred for mets components on nafld, with obesity having the greatest (16.37%) effect, followed by diabetes (10.85%), dyslipidemia (10.74%) and hypertension (7.36%). |
| PubMedID- 22087177 | nafld is frequently associated with obesity, diabetes mellitus and the metabolic syndrome. |
| PubMedID- 24130687 | Several studies have suggested that vitamin d deficiency and nafld are commonly associated with central obesity and insulin resistance [2], [8], [9]. |
| PubMedID- 20370671 | nafld is strongly associated with obesity, insulin resistance, hypertension and dyslipidaemia and is now regarded as the liver manifestation of the metabolic syndrome. |