eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | metabolic syndrome x |
| Comorbidity | |obesity |
| Sentences | 300 |
| PubMedID- 21187867 | Objective: the present community-based cross-sectional study was aimed to examine the association of metabolic syndrome (ms) with obesity measures, metabolic profiles, and intake of dietary fatty acids in asian indian population. |
| PubMedID- 21276250 | This would be relevant to many developing countries with poor resources, such as those in south asia, which are battling rapid increases in diabetes, obesity and other components of the metabolic syndrome. |
| PubMedID- 25965509 | Fructose has been confirmed to induce several obesity-related complications associated with the metabolic syndrome. |
| PubMedID- 21884160 | This paper reviews epidemiological evidence demonstrating the association between chronic social stress and development of obesity and symptoms leading to metabolic syndrome. |
| PubMedID- 20944981 | Central obesity is associated with osas and metabolic syndrome, and there is evidence that obstructive sleep apnea is an independent risk factor for obesity, glucose intolerance and insulin resistance. |
| PubMedID- 21385419 | These findings provide important insight and implications for preventing and treating obesity associated with metabolic syndrome. |
| PubMedID- 24270951 | These transitional nutrition regions are very relevant to this type of research because these areas contain a large number of children with low birth weights who are further exposed to diets containing foods of low cost, high caloric value, and low nutrient quality, which may increase the incidence of obesity and diseases associated with metabolic syndrome (9). |
| PubMedID- 21711426 | Increasing age, obesity and the presence of multiple features of metabolic syndrome, especially diabetes, are associated with a higher probability of having non-alcoholic steatohepatitis (nash). |
| PubMedID- 24904871 | Another study reported that hypothalamic obesity is associated with metabolic syndrome and cardiovascular morbidity without increased insulin sensitivity36). |
| PubMedID- 25769350 | Therefore, a proanthocyanidin-rich diet during obesity can improve some of the metabolic syndrome symptoms at least at the molecular level. |
| PubMedID- 25875942 | Non-alcoholic fatty liver disease (nafld) is the most common cause of hepatic disease in western civilization [1] and is considered as a hepatic manifestation of a metabolic syndrome strongly associated with dyslipidemia, obesity, hypertension and insulin resistance[2]. |
| PubMedID- 21754922 | Ffas cause insulin resistance in all major insulin target organs (skeletal muscle, liver, and endothelial cells) and have emerged as a major link between obesity, the development of the metabolic syndrome, and atherosclerotic vascular disease [11]. |
| PubMedID- 24334572 | Objective: both increased serum levels of low-density lipoprotein cholesterol (ldlc) and metabolic syndrome (mets) are associated with obesity and have been established to be risk factors of cardiovascular disease. |
| PubMedID- 21688564 | Nafld as the hepatic manifestation of the metabolic syndrome (ms) is associated with obesity, diabetes mellitus and dislipidemia. |
| PubMedID- 23734506 | [age dependence of metabolic syndrome association with obesity types among women]. |
| PubMedID- 20156345 | Sedentary behaviour, such as time spent sitting is positively associated with coronary heart disease risk factors, obesity, and development of the metabolic syndrome [3,4]. |
| PubMedID- 20180954 | It is however pertinent to note that although the specific role of central obesity in patients with the metabolic syndrome remains unexplained, active brown adipocytes which accumulate in central locations have been found to be metabolically active. |
| PubMedID- 24815358 | metabolic syndrome, including obesity, diabetes/insulin resistance, hypertension and dyslipidemia is a major threat for public health in the modern society. |
| PubMedID- 21711372 | Objective: obesity is strongly associated with metabolic syndrome, but not all obese individuals display a clustering of metabolic risk factors. |
| PubMedID- 24410812 | Lactoferrin (lf), a multifunctional glycoprotein in mammalian milk, is reported to exert a modulatory effect on lipid metabolism and improve visceral fat-type obesity, an underlying cause of the metabolic syndrome. |
| PubMedID- 26078820 | Nafld, as a hepatic manifestation of metabolic syndrome, is associated with dyslipidemia, obesity, insulin resistance, and type 2 diabetes mellitus [1, 2]. |
| PubMedID- 20846382 | It is also relevant to mention that as reaven found insulin resistant individuals who were not obese, he did not include obesity as a feature of the insulin resistance syndrome. |
| PubMedID- 25594826 | Sarcopenic obesity with metabolic syndrome: a newly recognized entity following living donor liver transplantation. |
| PubMedID- 22937748 | Reported cutoff points for waist circumference and their predictive value for abdominal obesity and risk of metabolic syndrome (mets) in the chinese population [13]. |
| PubMedID- 23208524 | Nafld may represent the hepatic manifestation of the metabolic syndrome with visceral obesity, dyslipidaemia, and insulin resistance [198]. |
| PubMedID- 23714599 | Background: opinions differ over the exercise modalities that best limit cardiovascular risk (cvr) resulting from visceral obesity in individuals with metabolic syndrome (mets). |
| PubMedID- 20129610 | The risk of obesity-induced metabolic syndrome is higher in asians than in caucasians. |
| PubMedID- 26474291 | Next, obesity often coincides with metabolic syndrome (mets), type 2 diabetes (t2d) and chronic inflammation in varying degrees. |
| PubMedID- 25760026 | Insulin resistance is a common pathological state found in the metabolic syndromeassociated with obesity and type 2 diabetes mellitus, in which target tissues fail torespond properly to physiologic insulin levels (5,7). |
| PubMedID- 25714610 | With more than 1.4 billion overweight or obese adults worldwide, obesity and progression of the metabolic syndrome are major health and economic challenges. |
| PubMedID- 26096168 | metabolic syndrome is characterized with abdominal obesity, insulin resistance, dyslipidemia and hepatic dysfunction. |
| PubMedID- 26558034 | The latter must be viewed as a novel renal manifestation of insulin resistance in the context of metabolic syndrome with central obesity as its primary key feature. |
| PubMedID- 26473366 | Both insulin resistance and central obesity predict the development of metabolic syndrome, which increases the risks of type 2 diabetes, hyperlipidemia, and cardiovascular disease [6–8]. |
| PubMedID- 20224753 | It is also recognized that many subjects with osa have central obesity and other features of metabolic syndrome [39], which is most widely accepted as being comprised of hyperinsulinemia, glucose intolerance, dyslipidemia, central obesity, and hypertension [58]. |
| PubMedID- 22744625 | The aim of our study was to investigate if vitamin d deficiency without diabetes mellitus and metabolic syndrome is associated with obesity and abdominal obesity. |
| PubMedID- 24222915 | Hypogonadism in men is associated with insulin resistance [5], visceral obesity, the risk of metabolic syndrome [22, 23], vascular complications of diabetes [24], and risk for developing type 2 diabetes [6, 24]. |
| PubMedID- 20615436 | Leptin, adiponectin and ghrelin were more closely related to insulin resistance and central obesity as core components of the metabolic syndrome. |
| PubMedID- 26469529 | obesity is associated with the metabolic syndrome. |
| PubMedID- 26504474 | These results suggest that bc ameliorated dyslipidemia, hypertension, insulin resistance, and obesity in rats with hf-induced metabolic syndrome. |
| PubMedID- 26554109 | The aim of this study was to determine the relationships between serum adiponectin levels and parameters of both insulin sensitivity and obesity in patients with the metabolic syndrome and/or coronary artery disease, as well as to assess predictive value of adiponectin serum levels as a biomarker of these entitetis. |
| PubMedID- 25885657 | Participants satisfying the full criteria will be classified as having metabolic syndrome; whereas those with central obesity (waist circumference >94 cm men or >80 cm women [europids, sub-saharan africans, eastern mediterranean, middle east]; >90 cm men or >80 cm women [south asians, chinese, japanese]) plus any one of: raised triglyceride level (>1.7 mm, or treatment for this); reduced hdl-cholesterol (<1.03 mm in males and <1.29 mm in females, or treatment for this); will be classified as being at risk of metabolic syndrome. |
| PubMedID- 24674634 | Results from screenings identified high obesity rates, high prevalence of metabolic syndrome, low fruit and vegetable consumption, and low use of preventive medical therapies as interventions for priority risk factors (12,13). |
| PubMedID- 26063458 | metabolic syndrome is linked with obesity and is often first identified clinically by elevated bmi and elevated levels of fasting blood glucose that are generally secondary to insulin resistance. |
| PubMedID- 23900353 | Hyperuricemia and its association with obesity and various components of metabolic syndrome have been documented in previous studies. |
| PubMedID- 19863955 | Background: in obese patients, positioning of the bioenterics intragastric balloon (bib) proved beneficial for weight loss, but the effect of the device on ameliorating some components of the metabolic syndrome associated with obesity remains uncertain. |
| PubMedID- 22662254 | Transgenic over-expression of 11β-hsd1 in adipose tissue recapitulates the metabolic syndrome in mice, with visceral obesity, dyslipidemia, insulin resistance/diabetes and hypertension [2], [5]. |
| PubMedID- 20576133 | Childhood obesity heightens childhood risk of metabolic syndrome, indicating that prevention of early onset obesity may substantially reduce the prevalence of metabolic syndrome in youth and their future risk of life-threatening conditions such as diabetes and cardiovascular disease [4]. |
| PubMedID- 25995613 | The rest of the components of metabolic syndrome, including obesity, elevated triglycerides, low hdl, and fasting glucose, were seen in equal prevalence among diabetics with and without diabetic retinopathy and among diabetics with npdr and pdr (figure 1, tables 2 and 3). |
| PubMedID- 25885910 | Overweight and obesity, the epicenter of the metabolic syndrome, are the most important risk factors for diabetes [4-6]. |
| PubMedID- 25055476 | Bmi does not allow to distinguish lean body mass from fat mass and therefore to evaluate abdominal obesity which is associated with metabolic syndrome and cv risk. |