eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | metabolic syndrome x |
| Comorbidity | |diabetes |
| Sentences | 158 |
| PubMedID- 21446088 | Conclusion: administration of metformin in type 2 diabetes with metabolic syndrome decreased cardiovascular risk factors by reducing glycemia, triglycerides, bmi, central obesity and insulin resistance. |
| PubMedID- 19837794 | All the analyses presented so far used the national cholesterol education program definition but were repeated using the international diabetes federation definition (http://www.idf.org/metabolic_syndrome) of metabolic syndrome. |
| PubMedID- 24741576 | In the literature, it has been described that plasma il-6 levels are associated with increased cv risk and observed in sle patients with metabolic syndrome [53] and in patients with type 2 diabetes [44, 54]. |
| PubMedID- 22144985 | This in utero programming seems to create a kind of “metabolic memory,” since physiological anomalies of gestational period are responsible for the onset of diseases in offspring at adulthood, such as type 2 diabetes and obesity associated with metabolic syndrome. |
| PubMedID- 20927114 | Therefore, we focused on the spontaneously hypertensive corpulent rat (shr/n-cp), a model with type 2 diabetes, obesity and features of the metabolic syndrome to characterize retinal changes at a structural and functional level. |
| PubMedID- 24168442 | As insulin resistance, raised fasting and postprandial insulin levels, impaired carbohydrate tolerance and, ultimately, diabetes (all components of the metabolic syndrome) have been related to increased cardiovascular risk, in this report we review the potential role that individual nutrients, foods/food groups, and dietary patterns play in insulin sensitivity and secretion in the management of metabolic syndrome. |
| PubMedID- 20197633 | Sldl-c, ldl-c and hs-crp were the highest and hdl-c was lowest in the metabolic syndrome with diabetes group. |
| PubMedID- 25053801 | Conclusions: the proinflammatory state associated with metabolic syndrome in patients with type 1 diabetes leads to deterioration of glycaemic control and an increase in the required daily dose of insulin. |
| PubMedID- 20835560 | Santos et al.1 evaluated the frequency of metabolic syndrome among adults with type 1 diabetes mellitus according to the criteria of the international diabetes federation, the national cholesterol education program, and the world health organization and concluded that the latter set of criteria may be preferable in identifying patients in this group, because of better sensitivity. |
| PubMedID- 20028945 | Changes in adipose tissue distribution could accompany significant improvements in the components of the metabolic syndrome in individuals with type 2 diabetes (35–36); however, we did not find that the relationships specifically between improvements in the adipose tissue distribution and improvements in the peripheral insulin sensitivity were independent of the change in overall weight and adipose tissue mass. |
| PubMedID- 25739820 | Although several cross-sectional studies linked nonalcoholic fatty liver disease to either diabetes and other components of the metabolic syndrome, we focused on 28 longitudinal studies which provided evidence for nonalcoholic fatty liver disease as a risk factor for the future development of diabetes. |
| PubMedID- 21270197 | In a cox regression model, it remained significantly associated with an increased risk for incident diabetes, when the presence of metabolic syndrome was introduced as a covariate: the hrs in the highest endotoxin quartiles were 1.650 (95% ci 1.210–2.250, p = 0.002) (table 3) and 1.701 (1.249–2.316, p = 0.001) depending on the metabolic syndrome definition, atp iii or idf, respectively. |
| PubMedID- 24103901 | Prevention of type 2 diabetes in subjects with prediabetes and metabolic syndrome treated with phentermine and topiramate extended release. |
| PubMedID- 20666270 | We sought to determine the impact of the metabolic syndrome, defined with international diabetes federation criteria, on arterial pulse wave velocity. |
| PubMedID- 24054926 | Inconsistencies or gaps were particularly obvious for studies of sex or gender differences in age and optimal measures of body size for chd outcomes, and in the striking interface of diabetes and people with the metabolic syndrome, most of whom have unrecognized diabetes. |
| PubMedID- 19897788 | Association between retinol-binding protein 4 concentrations and gestational diabetes mellitus and risk of developing metabolic syndrome after pregnancy. |
| PubMedID- 23250798 | Objective: to analyze the participation of fatty liver (fl) in the association of metabolic syndrome (ms) with type 2 diabetes and coronary artery calcification (cac). |
| PubMedID- 21829540 | We compared two risk-stratification approaches for incident type 2 diabetes mellitus (t2dm); factors of metabolic syndrome (mets) and a previously developed diabetes risk score, predx® diabetes risk score (drs). |
| PubMedID- 20504294 | Since hypertension and type ii diabetes mellitus are components of the metabolic syndrome or insulin resistance syndrome, our gouty men are likely to have this syndrome that carries an increased cardiovascular risk [46]. |
| PubMedID- 23728331 | Type 2 diabetes mellitus with metabolic syndrome developed at 30 weeks of age, and the body weights and plasma insulin levels of oletf rats at 60 weeks of age were lower than those of normal rats. |
| PubMedID- 21145931 | These processes are important in diabetes and other facets of the metabolic syndrome, which represents a considerable increasing health burden. |
| PubMedID- 25940982 | Therefore, a cordycepin treatment during diabetes can improve some of the metabolic syndrome symptoms by regulation of glucose absorption in vivo. |
| PubMedID- 25993638 | Increased cardiovascular mortality in subjects with metabolic syndrome is largely attributable to diabetes and hypertension in 159,971 korean adults. |
| PubMedID- 22701848 | [1112] since metformin is useful for management of diabetes cases with metabolic syndrome, which is a risk factor for sleep apnea,[1314] hence, metformin is helpful for preventing sleep apnea. |
| PubMedID- 24159331 | diabetes mellitus, development of metabolic syndrome, increased risk of death due to cardiovascular diseases, and pathologic bone fractures due to severe loss of bone are well-known negative effects of iatrogenic or spontaneous t depletion [21, 22]. |
| PubMedID- 22291496 | diabetes mellitus is part of the insulin resistance syndrome (irs), which includes hypertension, dyslipidemia, and obesity as its other components. |
| PubMedID- 22486725 | Conclusions: inppl1 gene variants may contribute to susceptibility to the metabolic syndrome in men with type 1 diabetes, but not to diabetic nephropathy. |
| PubMedID- 24818164 | Management of cardiorenal metabolic syndrome in diabetes mellitus: a phytotherapeutic perspective. |
| PubMedID- 24266721 | Relationship between smoking and metabolic syndrome in men with diabetes mellitus. |
| PubMedID- 25885920 | International diabetes federation (idf) criteria of metabolic syndrome [22]; median basal value: 95 mg/dl; range: 65–243 mg/dl), bp (cut-off 130 mm/hg for systolic pressure and 85 mm/hg for diastolic pressure sec. |
| PubMedID- 20940070 | Objective: we examined the risk of cardiovascular disease, stroke, ischaemic heart disease, and diabetes with the metabolic syndrome according to the new harmonised definition and its components using a national longitudinal data set from an asian population. |
| PubMedID- 26280008 | The association between periodontal disease and metabolic syndrome among outpatients with diabetes in jordan. |
| PubMedID- 21890532 | Aims: methylglyoxal (mg) overproduction has been reported in metabolic syndrome with hyperglycaemia (diabetes) or without hyperglycaemia (hypertension), and the underlying mechanism was investigated. |
| PubMedID- 20424809 | Prevalence of metabolic syndrome with international diabetes federation criteria and atp iii program in patients 65 years of age or older. |
| PubMedID- 21437109 | The us national cholesterol education program adult treatment panel iii (ncep-atp iii) defined central obesity as wc ≥ 102 cm in males and ≥88 cm in females.49 the 2005 international diabetes federation consensus definition of the metabolic syndrome used ethnic-specific cutpoints for waist circumference.50 a wc cutoff of 80–85 cm for men and 75–80 cm for women of korean or asian–pacific background was suggested.3,51 in other studies,2,52 a cutoff value of 0.5 for whtr has been proposed as a boundary value. |
| PubMedID- 20446581 | The cvd mortality of metabolic syndrome with diabetes is higher than those of metabolic syndrome without diabetes (hr, 3.67 vs 1.61). |
| PubMedID- 23484675 | Applying laws of biology to diabetes with emphasis on metabolic syndrome. |
| PubMedID- 21272190 | Aim: we examined the effects of the 11beta-hydroxysteroid dehydrogenase type 1 (hsd1) inhibitor, mk-0916, on the multiple components of the metabolic syndrome (mets) in patients with type 2 diabetes (t2dm) and mets. |
| PubMedID- 21994081 | Long-term effect of metabolic syndrome with and without diabetes mellitus on coronary revascularization in japanese patients undergoing percutaneous coronary intervention. |
| PubMedID- 20472485 | Those who have the metabolic syndrome with or without diabetes suffer more often from dysexecutive problems and slower psychomotor speed than do other patients. |
| PubMedID- 25435604 | Conclusion: our study suggests that diabegon could be included as a preventive treatment in metabolic syndrome subjects with type 2 diabetes especially for long term treatment as it efficiently shows anti-hyperglycemic and anti-lipidemic effects with no adverse impacts on the liver and kidney. |
| PubMedID- 19690575 | Snp276g>t polymorphism in the adiponectin gene is associated with metabolic syndrome in patients with type ii diabetes mellitus in korea. |
| PubMedID- 24696694 | The international diabetes federation (idf) definition of metabolic syndrome (mets) includes the presence of central obesity, wc > 80 cm, with any of the two following: hypertension > 130/85 mmhg, fpg >5.6 mmol/l, tg > 1.7 mmol/l, and hdl < 1.3 mmol/l (14). |
| PubMedID- 22669833 | Relationship between serum testosterone levels and features of the metabolic syndrome defining criteria in patients with type 2 diabetes mellitus. |
| PubMedID- 21205020 | Objectives: to examine whether interleukin-1 receptor antagonist (il-1ra) is a predictor for clinically incident diabetes in subjects with metabolic syndrome (mets) and whether its predictive power is independent of c-reactive protein (crp), an established marker of inflammation. |
| PubMedID- 22550482 | In general, stone disease is often associated with diabetes, a part of the metabolic syndrome [4–6]. |
| PubMedID- 21993838 | Thus, pai-1 plays a critical role in the insulin resistance syndrome, which leads to type 2 diabetes mellitus, and is associated with its side effects such as an increased risk of diabetic nephropathy, atherosclerotic cardiovascular disease and others. |
| PubMedID- 22419057 | Obesity, diabetes, and other components of the metabolic syndrome are frequently associated with the nafld. |
| PubMedID- 20966915 | Cd36 variants have been associated with type 2 diabetes, features of the metabolic syndrome, and alterations in lipid metabolism. |
| PubMedID- 21785747 | [30] reported that diabetes patients with metabolic syndrome are more at risk for cardiovascular disease than diabetes patients without metabolic syndrome. |