eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | c syndrome |
| Comorbidity | |diabetes |
| Sentences | 163 |
| PubMedID- 22762010 | Serum levels of c-peptide are associated with the metabolic syndrome in patients with type 2 diabetes and in diabetic patients with nephropathy and vascular disease [37]. |
| PubMedID- 21890532 | Aims: methylglyoxal (mg) overproduction has been reported in metabolic syndrome with hyperglycaemia (diabetes) or without hyperglycaemia (hypertension), and the underlying mechanism was investigated. |
| PubMedID- 24708638 | Our previous study showed that nc is a good predictor of metabolic syndrome in patients with type 2 diabetes [3]. |
| PubMedID- 22328881 | The studies incorporated in the present analysis are:assessing the treatment effect in metabolic syndrome without perceptible diabetes (attempt) study, which included patients with mets but no dm or cvd [17];implementation of strategy for the management of overt dyslipidemia (improve-dyslipidemia) study, which included patients with dyslipidaemia with or without dm, with or without cvd [20];standardized arrangement for a guideline-driven treatment of the metabolic syndrome (sage-mets) study, which included patients with mets but no cvd [21];implementation of guidelines for the management of arterial hypertension (impulsion) study, which included patients with hypertension with or without dm but no cvd [22];initiative for a new diabetes therapeutic approach in a mediterranean country (indeed) study, which included patients with diabetes but no cvd [23]. |
| PubMedID- 23962041 | Periodic surveillance for diabetes and features of the metabolic syndrome should be undertaken in obese individuals as is recommended for obesity in the general population. |
| PubMedID- 20586225 | The consequence is a metabolic syndrome with type 2 diabetes and increased cardiovascular mortality. |
| PubMedID- 24381639 | On the other hand, high uric acid levels might predict the development of metabolic syndrome consequentially leading to diabetes [7, 8] and can also increase severity of the already developed disease by leading to a higher incidence of certain diabetic complications [9]. |
| PubMedID- 24696694 | The international diabetes federation (idf) definition of metabolic syndrome (mets) includes the presence of central obesity, wc > 80 cm, with any of the two following: hypertension > 130/85 mmhg, fpg >5.6 mmol/l, tg > 1.7 mmol/l, and hdl < 1.3 mmol/l (14). |
| PubMedID- 24843614 | Furthermore, some studies showed that fish intake reduced the rates of incidence for diabetes in patients with metabolic syndrome, and reduced the rates of death in patients with type 2 diabetes13,14. |
| PubMedID- 20820795 | At last assessment, the prevalence of metabolic syndrome (international diabetes federation) was 17% in the sertindole group and 26% in the risperidone group and the incidence of metabolic syndrome was 7% in the sertindole group and 10% in the risperidone group. |
| PubMedID- 26558285 | These findings suggest that enhanced glycolysis and the tca cycle might contribute to the development of diabetes associated with metabolic syndrome. |
| PubMedID- 22417140 | Recent research has begun to elucidate the effects of hypothalamic inflammation in causing diverse components of metabolic syndrome leading to diabetes and cardiovascular disease. |
| PubMedID- 23115071 | Introduction: at present, little data exists about the incidence of, and the risk factors associated with, metabolic syndrome (mets) in patients with type 2 diabetes mellitus (t2dm). |
| PubMedID- 21749444 | Methods: cox models were developed to assess the risk of new-onset diabetes associated with the metabolic syndrome after adjusting for a priori confounders (age, sex, ethnicity and concomitant use of non-cardiovascular medications), its individual components and other determinants of new-onset diabetes. |
| PubMedID- 24408226 | Nephrotic syndrome complicated by idiopathic central diabetes insipidus. |
| PubMedID- 22295727 | Other factors associated with less favorable ldl goal attainment were coronary heart disease, carotid artery disease, diabetes, 10-year risk of > 20%, and metabolic syndrome (p < 0.05 for all). |
| PubMedID- 19837794 | All the analyses presented so far used the national cholesterol education program definition but were repeated using the international diabetes federation definition (http://www.idf.org/metabolic_syndrome) of metabolic syndrome. |
| PubMedID- 23304462 | Metabolic health was defined using the international diabetes federation definition of metabolic syndrome, excluding waist circumference (wc) criteria [22]. |
| PubMedID- 21055836 | Methods: 150 men were recruited from a genetic screening programme for hereditary hemocromatosis (hh) and were tested for type 2 diabetes, other components of the metabolic syndrome, beta cell function (bcf), insulin sensitivity, high-sensitivity c-reactive protein and iron overload. |
| PubMedID- 25782325 | [clinical evaluation of the influence of certain initial status parameters on the development of type 2 diabetes mellitus in patients with metabolic syndrome]. |
| PubMedID- 24339286 | Prognostic usefulness of metabolic syndrome compared with diabetes in korean patients with critical lower limb ischemia treated with percutaneous transluminal angioplasty. |
| PubMedID- 21165705 | Our results might indicate the possible role of cortisol in pathogenesis of type 2 diabetes mellitus in patients with metabolic syndrome as well as possible protective role of dhea-s within the frame of secondary contraregulatory mechanisms aimed to improve insulin sensitivity and reduce the hyperinsulinemia. |
| PubMedID- 21415918 | In the metabolic syndrome patients without overt diabetes mellitus, cystatin c levels were found to be elevated and the elevation was more pronounced in the subgroup with silent ischemia. |
| PubMedID- 22550482 | In general, stone disease is often associated with diabetes, a part of the metabolic syndrome [4–6]. |
| PubMedID- 21315688 | Taken together, these results may provide evidence of the therapeutic potential of kr-66344, as a 11beta-hsd1 inhibitor, in obesity and type 2 diabetes patients with metabolic syndrome. |
| PubMedID- 24595022 | We used the international diabetes federation's definition of metabolic syndrome [19]. |
| PubMedID- 22322078 | Pre-diabetes commonly associates with the metabolic syndrome. |
| PubMedID- 21894292 | Background: nonalcoholic fatty liver disease (nafld) is a clinic-pathological syndrome closely associated with obesity, dyslipidemia, diabetes and atherosclerosis. |
| PubMedID- 21061066 | The international diabetes federation (idf) definition of the metabolic syndrome of those from south and south-east asian are; central obesity (defined as waist circumference) ≥80 cm, plus any two of the following four factors: raised triglycerides; ≥1.7 mmol/l, reduced hdl-cholesterol <1.29 mmol/l in females, raised blood pressure; systolic bp ≥130 or diastolic bp ≥85 mmhg, or impaired fasting glycaemia (ifg); fasting plasma glucose ≥5.6 mmol/l [3–5]. |
| PubMedID- 20529259 | The international diabetes federation (idf) definition of the metabolic syndrome is [15]: central obesity (waist circumference ≥ 94 cm in men, ≥ 80 cm in women) and at least two of the following factors: (1) triglycerides ≥ 1.70 mmol/l or specific treatment for this lipid abnormality; (2) hdl-cholesterol < 1.03 mmol/l in men and < 1.29 mmol/l in women or specific treatment for this lipid abnormality; (3) systolic blood pressure ≥ 130 mm hg or diastolic blood pressure ≥ 85 mm hg or treatment for previously diagnosed hypertension; (4) fasting plasma glucose ≥ 5.6 mmol/l or previously diagnosed type 2 diabetes. |
| PubMedID- 25739820 | Although several cross-sectional studies linked nonalcoholic fatty liver disease to either diabetes and other components of the metabolic syndrome, we focused on 28 longitudinal studies which provided evidence for nonalcoholic fatty liver disease as a risk factor for the future development of diabetes. |
| PubMedID- 25878665 | A key strategy in preventing and treating diabetes and other components of metabolic syndrome should be prevention. |
| PubMedID- 20927114 | Therefore, we focused on the spontaneously hypertensive corpulent rat (shr/n-cp), a model with type 2 diabetes, obesity and features of the metabolic syndrome to characterize retinal changes at a structural and functional level. |
| PubMedID- 25699225 | diabetes is a group of metabolic syndromes and falls into two groups. |
| PubMedID- 20666270 | We sought to determine the impact of the metabolic syndrome, defined with international diabetes federation criteria, on arterial pulse wave velocity. |
| PubMedID- 21346069 | Results: the seven probands showed a severe partial lipodystrophic syndrome with diabetes and/or acanthosis nigricans, liver steatosis, hypertriglyceridemia, and low serum leptin and adiponectin levels. |
| PubMedID- 25940982 | Therefore, a cordycepin treatment during diabetes can improve some of the metabolic syndrome symptoms by regulation of glucose absorption in vivo. |
| PubMedID- 21829540 | We compared two risk-stratification approaches for incident type 2 diabetes mellitus (t2dm); factors of metabolic syndrome (mets) and a previously developed diabetes risk score, predx® diabetes risk score (drs). |
| PubMedID- 22486725 | Conclusions: inppl1 gene variants may contribute to susceptibility to the metabolic syndrome in men with type 1 diabetes, but not to diabetic nephropathy. |
| PubMedID- 24740690 | Particularly, due to the pathophysiological relevance of acc2 in lipid metabolic syndrome associated with obesity, diabetes, cancer, and cardiovascular disease, acc2 activity regulation has been considered as a candidate target for therapeutic interventions, which essentially requires authentic bioengineered recombinant proteins (abu-elheiga et al. |
| PubMedID- 25435604 | Conclusion: our study suggests that diabegon could be included as a preventive treatment in metabolic syndrome subjects with type 2 diabetes especially for long term treatment as it efficiently shows anti-hyperglycemic and anti-lipidemic effects with no adverse impacts on the liver and kidney. |
| PubMedID- 21270197 | In a cox regression model, it remained significantly associated with an increased risk for incident diabetes, when the presence of metabolic syndrome was introduced as a covariate: the hrs in the highest endotoxin quartiles were 1.650 (95% ci 1.210–2.250, p = 0.002) (table 3) and 1.701 (1.249–2.316, p = 0.001) depending on the metabolic syndrome definition, atp iii or idf, respectively. |
| PubMedID- 21423737 | Both obesity and diabetes are features of the metabolic syndrome, which increases ones risk for cardiovascular diseases. |
| PubMedID- 22370155 | The influence on the prevalence of metabolic syndrome was greater with the international diabetes federation (idf) criteria (19.3-23.9% in men and 29.4-43.1% in women) than with the adult treatment panel iii (atp iii) criteria (26.1-28.6% in men and 37.3-44.1% in women). |
| PubMedID- 21688564 | Nafld as the hepatic manifestation of the metabolic syndrome (ms) is associated with obesity, diabetes mellitus and dislipidemia. |
| PubMedID- 22419057 | Obesity, diabetes, and other components of the metabolic syndrome are frequently associated with the nafld. |
| PubMedID- 24168442 | As insulin resistance, raised fasting and postprandial insulin levels, impaired carbohydrate tolerance and, ultimately, diabetes (all components of the metabolic syndrome) have been related to increased cardiovascular risk, in this report we review the potential role that individual nutrients, foods/food groups, and dietary patterns play in insulin sensitivity and secretion in the management of metabolic syndrome. |
| PubMedID- 24266721 | Relationship between smoking and metabolic syndrome in men with diabetes mellitus. |
| PubMedID- 24376641 | Addition of framingham risk score or replacement of diabetes with metabolic syndrome in this model did not change the results (p = 0.017 and p = 0.009). |
| PubMedID- 22007026 | This post hoc analysis of the assessing the treatment effect in metabolic syndrome without perceptible diabetes (attempt) study assesses the 3(1/2) year incidence of new-onset diabetes (nod) and related cardiovascular disease (cvd) events in patients with metabolic syndrome (mets), after multifactorial (lifestyle and drug, including atorvastatin) intervention. |