eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | non-alcoholic fatty liver disease |
| Comorbidity | |obesity |
| Sentences | 164 |
| PubMedID- 24358267 | obesity is associated with nonalcoholic fatty liver disease (nafld) [3]. |
| PubMedID- 20602679 | Therefore, we examined the appropriate cutoff points of abdominal obesity indices associated with nafld in korean men and women using receiver operating characteristic (roc) curve analysis. |
| PubMedID- 21325464 | Introduction: triglyceride accumulation in the liver is an early feature in the development of nonalcoholic fatty liver disease (nafld) associated with human obesity, which is a multifactorial syndrome and whose underlying mechanisms are beginning to be understood. |
| PubMedID- 24528352 | Non alcoholic fatty liver disease (nafld) is associated with obesity, insulin resistance (ir) and increased type 2 diabetes (t2d). |
| PubMedID- 22209679 | Background & aims: non-alcoholic fatty liver disease (nafld) is commonly associated with obesity, metabolic syndrome and type 2 diabetes. |
| PubMedID- 21423719 | In epidemiologic studies nafld is associated with increased central obesity, higher low density lipoprotein (ldl)- cholesterol and lower high density lipoprotein (hdl)-cholesterol levels, impaired fasting glucose, increased risk of diabetes and increased insulin resistance. |
| PubMedID- 23951308 | nonalcoholic fatty liver disease is associated with obesity and insulin resistance. |
| PubMedID- 25937862 | nafld is associated with obesity and insulin resistance and is considered the hepatic manifestation of the metabolic syndrome, a combination of medical conditions including type 2 diabetes mellitus, hypertension, hyperlipidemia, and visceral adiposity. |
| PubMedID- 24788149 | Population studies show that nafld is strongly associated with obesity, dyslipidemia, insulin resistance, and hypertension. |
| PubMedID- 22201932 | non alcoholic fatty liver disease (nafld) is associated with obesity, diabetes and insulin resistance (ir). |
| PubMedID- 22187655 | nafld is associated with insulin resistance, obesity, and a lifestyle characterized by physical inactivity and an unlimited supply of high-fat foods. |
| PubMedID- 20604719 | Background and aims: non-alcoholic fatty liver disease (nafld) is strongly associated with obesity and diabetes mellitus. |
| PubMedID- 21841322 | We hypothesized that dhea is involved in the pathophysiology of non-alcoholic fatty liver disease (nafld) often associated with obesity and insulin resistance. |
| PubMedID- 24713801 | Background: although non-alcoholic fatty liver disease (nafld) is associated with obesity and metabolic syndrome (ms), it may also be present in lean individuals. |
| PubMedID- 20459722 | nafld is associated with obesity, the metabolic syndrome, dyslipidemia, insulin resistance, and type 2 diabetes [1]. |
| PubMedID- 26151226 | nafld is often associated with obesity, insulin resistance, and diabetes. |
| PubMedID- 23939604 | nonalcoholic fatty liver disease is associated with physical inactivity, obesity, and metabolic syndrome. |
| PubMedID- 23304464 | nafld is associated with morbid obesity, type 2 diabetes, and hyperlipidaemia; however, excess alcohol intake is still the main cause of fatty liver disease. |
| PubMedID- 25591123 | Morbid obesity is strongly associated with nonalcoholic fatty liver disease (nafld), which is one of the most common causes of chronic liver disease worldwide. |
| PubMedID- 20798858 | Although an optimal management program for nafld in obesity and insulin resistance has not been established, some strategies are based on hypoglycemic and triglyceride-lowering agents and on lifestyle intervention through a low fat diet, vitamin e supplementation, and exercise [7]. |
| PubMedID- 24274869 | nafld is associated with central obesity, insulin resistance, type 2 diabetes, hypertension, and obesity-related dyslipidemia. |
| PubMedID- 26028579 | Background & aims: the prevalence of nonalcoholic fatty liver disease (nafld) has increased with the obesity pandemic. |
| PubMedID- 25797622 | Ob/ob mice provide an animal model for non-alcoholic fatty liver disease/non-alcoholic steatohepatitis (nafld/nash) in patients with obesity and type-2 diabetes. |
| PubMedID- 24786095 | nafld is strongly associated with obesity, which induces adipokine secretion, endoplasmic reticulum (er) and oxidative stress at the cellular level, which in turn induces hepatic steatosis, inflammation and fibrosis. |
| PubMedID- 21855538 | non-alcoholic fatty liver disease (nafld) is strongly associated with obesity and the metabolic syndrome. |
| PubMedID- 23929732 | The dag-pkc hypothesis can explain the occurrence of hepatic insulin resistance observed in most cases of nafld associated with obesity, lipodystrophy, and type 2 diabetes. |
| PubMedID- 20546964 | non-alcoholic fatty liver disease (nafld) is frequently associated with obesity in children. |
| PubMedID- 25536648 | Background: non-alcoholic fatty liver disease (nafld) is correlated with obesity, but specific therapeutic interventions are lacking. |
| PubMedID- 22720311 | Although obesity is closely associated with non-alcoholic fatty liver disease, the excess of visceral fat storage is reckoned to be just as or even more important. |
| PubMedID- 25500875 | Given that obesity is closely associated with nafld, we speculate that fxr may be downregulated or dysfunctional in the livers of obese individuals. |
| PubMedID- 22183113 | Purpose of review: steatosis or nonalcoholic fatty liver disease (nafld) is commonly associated with abdominal obesity and metabolic disorders. |
| PubMedID- 25490708 | Elevated ggt can signal liver injury generally, and non-alcoholic fatty liver disease associated with abdominal obesity and other features of the metabolic syndrome [39]. |
| PubMedID- 22768831 | Although obesity is associated with nonalcoholic fatty liver disease (nafld), the causal mechanisms are unclear. |
| PubMedID- 24454976 | However, 1 patient had, as in our case, a prior cardiovascular disease, which has been combined with obesity, frequently associated with nafld [18]. |
| PubMedID- 23304532 | Since nafld is closely associated with obesity, diabetes, and mets, it is unknown whether the relationship between nafld and all-cause mortality and cardiovascular death, if any, is independent of cardiometabolic risk factors (figure 1) such as mets and type 2 diabetes. |
| PubMedID- 24682220 | nafld is strongly associated with obesity, metabolic syndrome, diabetes and hyperlipidemia [24]. |
| PubMedID- 20222991 | The concept that the onset and development of nafld are associated with obesity and over-intake of calories, which are linked to oxidative stress and insulin resistance, is commonly accepted. |
| PubMedID- 19840251 | The aim of this study was to investigate whether any association or predictor effect of ad36 seropositivity is present in non-alcoholic fatty liver disease (nafld), a condition associated with obesity and insulin resistance (ir). |
| PubMedID- 25764541 | non-alcoholic fatty liver disease (nafld) is frequently associated with obesity and has become the most common cause of pediatric liver disease. |
| PubMedID- 24070151 | According to the obesity trend, the prevalence of pediatric nonalcoholic fatty liver disease (nafld) is also increasing. |
| PubMedID- 23935128 | Objective: adipose tissue-derived factors link non-alcoholic fatty liver disease (nafld) with obesity, which has also been reported for circulating chemerin. |
| PubMedID- 23431426 | Morbid obesity is strongly associated with nonalcoholic fatty liver disease (nafld) which is one of the most common causes of chronic liver disease worldwide. |
| PubMedID- 25285192 | Due to the high prevalence of obesity in subjects with nafld, obstructive sleep apnoea (osa) is very common and often unrecognised. |
| PubMedID- 24015600 | Population studies show that nafld is strongly associated with insulin resistance, obesity, type 2 diabetes mellitus, and lipid abnormalities. |
| PubMedID- 26011302 | Background: nonalcoholic fatty liver disease (nafld) is associated with obesity, type 2 diabetes mellitus, and dyslipidemia. |
| PubMedID- 22364559 | obesity-dependent metabolic signatures associated with nonalcoholic fatty liver disease progression. |
| PubMedID- 20460908 | non-alcoholic fatty liver disease (nafld) is commonly associated with obesity and diabetes, and is characterized by insulin resistance (ir). |
| PubMedID- 24550584 | Association of nafld with obesity, type 2 diabetes, and other metabolic syndrome suggests hyperglycemia, hyperlipidaemia, and insulin resistance as triggering factors in pathogenesis of nafld. |
| PubMedID- 24489777 | In summary, we penetratingly reported the curative role of ua on nafld with obesity for the first time. |
| PubMedID- 20186137 | Nonalcoholic fatty liver disease (nafld) is associated with obesity, insulin resistance, and impaired glucose tolerance. |