eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | non-alcoholic fatty liver disease |
| Comorbidity | |metabolic syndrome |
| Sentences | 102 |
| PubMedID- 24765691 | An association of non-alcoholic fatty liver disease with insulin resistant metabolic syndrome and hypothyroidism has been suggested. |
| PubMedID- 21698231 | non-alcoholic fatty liver disease (nafld) is associated with the metabolic syndrome, a cluster of factors associated with the development of insulin resistance and atherosclerosis which has reached epidemic proportions in the developed world [1]. |
| PubMedID- 25961500 | However, recent studies have shown that nafld is associated with components of metabolic syndrome such as insulin resistance, abdominal obesity and a proinflammatory state, and increases the risk of developing type 2 diabetes mellitus789. |
| PubMedID- 24424211 | non-alcoholic fatty liver disease (nafld) is associated with the metabolic syndrome, especially obesity, hyperlipidaemia and diabetes1, and is now the most common liver disease in both adults and children worldwide2. |
| PubMedID- 19880582 | Accumulating trans-sectional evidence suggests that the presence of multiple metabolic disorders, including obesity, diabetes, dyslipidemia, hypertension, and ultimately metabolic syndrome, are associated with nonalcoholic fatty liver disease (nafld) (1). |
| PubMedID- 20473151 | Advanced age, extensive overweight and a number of features of the metabolic syndrome are associated with nafld severity. |
| PubMedID- 21760736 | Bio f(1)b hamsters fed with a high-fat/high-cholesterol diet may thus be a good animal model for research on the treatment of diet-induced metabolic syndrome complicated by nonalcoholic fatty liver disease. |
| PubMedID- 23842720 | Non-alcoholic steatohepatitis (nash) is the progressive phenotype of non-alcoholic fatty liver disease associated with the metabolic syndrome. |
| PubMedID- 26120587 | nonalcoholic fatty liver disease relationship with metabolic syndrome in class iii obesity individuals. |
| PubMedID- 24772746 | The results from the study reinforced the well established clinical association of nafld with elements of metabolic syndrome (mets) including dyslipidemia, hypertension and obesity; as t2dm population with these co-morbid conditions had 38%, 17% and 14% higher risk respectively, for nafld. |
| PubMedID- 20467324 | Conversely, in patients with nafld associated with metabolic syndrome, imt values were significantly higher than in patients with nafld alone (0.85 +/- 0.16 mm, p < 0.005). |
| PubMedID- 25071314 | Could metabolic syndrome lead to hepatocarcinoma via non-alcoholic fatty liver disease. |
| PubMedID- 26308292 | Context: an excess circulating uric acid level, even within the normal range, is always comorbid with metabolic syndrome (ms), several of its components, and nonalcoholic fatty liver disease (nafld), which was regarded as hepatic manifestation of ms; however, these associations remain controversial. |
| PubMedID- 22844333 | nonalcoholic fatty liver disease is associated with metabolic syndrome. |
| PubMedID- 26193051 | nafld is strongly associated with metabolic syndrome, but several other entities play a role in the pathogenesis of nafld more than metabolic syndrome. |
| PubMedID- 22114515 | Therefore, nafld with and without metabolic syndrome can be associated with increased cimt and increased risk of cardiovascular events in patients with nafld incidentally diagnosed on abdominal ultrasonography. |
| PubMedID- 21212755 | nonalcoholic fatty liver disease is associated with the metabolic syndrome. |
| PubMedID- 24336007 | In our study, glycemic control was negatively associated with fa and ggtp activity, the markers of nafld in patients with metabolic syndrome [23]. |
| PubMedID- 25218670 | Suspected nafld associated with metabolic syndrome and all 5 of its components. |
| PubMedID- 23394097 | Wang and colleagues observed hypo-adiponectinemia and insulin resistance in chinese nafld patients with metabolic syndrome. |
| PubMedID- 23997767 | Recently, it has been established that nafld is commonly associated with metabolic syndrome, including type 2 diabetes, obesity, dyslipidemia, and hypertension and consequently is associated with cardiovascular mortality [6–10]. |
| PubMedID- 22808787 | The aim of review: to verify the role of nutrition in development of nonalcoholic fatty liver disease in patients with metabolic syndrome. |
| PubMedID- 22546752 | Gamma-glutamyl transferase: a marker of nonalcoholic fatty liver disease in patients with the metabolic syndrome. |
| PubMedID- 24206433 | The entire spectrum of nafld has been associated with metabolic syndrome. |
| PubMedID- 22303323 | nafld occurs commonly with the metabolic syndrome, linked to excessive triglyceride accumulation, which may be the result of insulin resistance. |
| PubMedID- 20485253 | Higher age, extensive overweight, and number of features of the metabolic syndrome are associated with nafld severity. |
| PubMedID- 25436098 | Due to association between nafld with metabolic syndrome and also metabolic syndrome with cardiovascular diseases, many studies were performed regarding this relationship. |
| PubMedID- 21118396 | Background: moderate alcohol consumption may have certain beneficial effects against non-alcoholic fatty liver disease, which is associated with metabolic syndrome. |
| PubMedID- 23829707 | Showed that serum ggt and triglycerides and obesity were predictors of nafld in patients with the metabolic syndrome (13). |
| PubMedID- 25941433 | non-alcoholic fatty liver disease (nafld) is closely associated with metabolic syndrome. |
| PubMedID- 24895482 | (13) a limitation of the mcd model is the absence of the metabolic syndrome associated with nash or nafld in humans; however, this model has been used in previous studies to suitably reproduce certain features of human nash. |
| PubMedID- 22824914 | In patients with metabolic syndrome, the prevalence of non-alcoholic fatty liver disease (nafld) is two- or three time higher than in general population (marchesini et al., 2003). |
| PubMedID- 21071306 | Recent findings linking the components of metabolic syndrome with nafld and the progression to nonalcoholic steatohepatitis will be reviewed; in particular, the role of visceral adipose tissue, insulin resistance, adipocytokines, oxidative stress and diminished antioxidants within the liver in the exacerbation of these conditions. |
| PubMedID- 21160985 | nafld is also associated with metabolic syndrome (mets) and is considered as the hepatic component of mets by some authors. |
| PubMedID- 20355234 | In contrast to ald, nafld is commonly associated with metabolic syndrome, obesity and insulin resistance. |
| PubMedID- 25844093 | nafld is closely associated with metabolic syndrome, abdominal obesity, and insulin resistance [3]. |
| PubMedID- 24018493 | Although the association of nafld with metabolic syndrome was identified by 91% of pcps, only 46% screened diabetic obese patients for nafld. |
| PubMedID- 21798002 | Consistent with the respondents comments, stickel et al, have described the increased incidence of hcc in patients with non-alcoholic fatty liver disease (nafld) which is associated with metabolic syndrome, obesity and insulin resistance [20]. |
| PubMedID- 26523205 | nafld is usually associated with the metabolic syndrome (ms), which is chiefly related to insulin resistance and its consequences. |
| PubMedID- 22644007 | Prevalence of nonalcoholic fatty liver disease in subjects with metabolic syndrome. |
| PubMedID- 23897104 | Background: the association of plasma cardiovascular risk markers and metabolic syndrome (mets) with non-alcoholic fatty liver disease (nafld) has not been well defined. |
| PubMedID- 21077793 | After stepwise linear regression analysis, serum zag concentrations were the only independent predictor of the number of metabolic syndrome components in patients with nafld (beta=0.22; t=2.001, p<0.05). |
| PubMedID- 22813407 | Association of nonalcoholic fatty liver disease with metabolic syndrome in indian population. |
| PubMedID- 22950055 | In addition, nafld is closely associated with metabolic syndrome, type 2 diabetes mellitus (t2dm) and cardiovascular morbidity and mortality. |
| PubMedID- 24682220 | nafld is strongly associated with obesity, metabolic syndrome, diabetes and hyperlipidemia [24]. |
| PubMedID- 20814441 | Nonalcoholic fatty liver disease (nafld) is associated with metabolic syndrome and insulin resistance [58]. |
| PubMedID- 26438057 | nafld is frequently associated with the metabolic syndrome (mes), of which it is considered the hepatic manifestation (vanni et al. |
| PubMedID- 22140316 | Conclusion: this study shows that pure nafld without metabolic syndrome in middle-aged subjects is strongly associated with morphological (cimt) and physiological (fmd) changes. |
| PubMedID- 26528424 | All of these findings suggest that nafld is closely associated with metabolic syndrome and it is now widely accepted that nafld is a hepatic manifestation of metabolic syndrome [14,18]. |
| PubMedID- 24223615 | The hamsters fed with hfd may thus be a good animal model for research on the treatment of diet-induced metabolic syndrome complicated by nafld [17]. |