eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | metabolic syndrome x |
| Comorbidity | |hypertension |
| Sentences | 114 |
| PubMedID- 23757400 | Shrs are a model of human essential hypertension with features of metabolic syndrome, including impaired glucose metabolism. |
| PubMedID- 20972515 | Urbanisation is associated with obesity, hypertension and development of the metabolic syndrome (ms). |
| PubMedID- 25159084 | Very often, obstructive sleep apnea (osa) and metabolic syndrome (ms) coexist with resistant hypertension (rhtn) and may lead to diastolic dysfunction. |
| PubMedID- PMC3113071 | Hyperglycemia, insulin resistance, hyperlipidemia and hypertension, which are components of metabolic syndrome, are also recognized as strong risk factors for cardiovascular disease [1]. |
| PubMedID- 23573411 | hypertension in metabolic syndrome: vascular pathophysiology. |
| PubMedID- 22304322 | [features of treatment of hypertension in patients with metabolic syndrome]. |
| PubMedID- 25306760 | [arterial hypertension in metabolic syndrome: pathophysiological aspects]. |
| PubMedID- 24288531 | Sympathetic nervous system overactivity is a key mechanism leading to hypertension in patients with the metabolic syndrome. |
| PubMedID- 20368993 | Our findings now suggest that seasonal weight gain bridges npas2 and hypertension to the pathogenesis of the metabolic syndrome. |
| PubMedID- 22829804 | The hope study showed a 22% reduction in cardiovascular events (mi, stroke, cardiac arrest, revascualrization, heart failure, death) in metabolic syndrome patients and without hypertension treated with an ace inhibitor, ramipril versus metabolic syndrome patients without hypertension not treated with an ace inhibitor [130]. |
| PubMedID- 22988490 | Diabetes, obesity, and metabolic syndrome may lead to pulmonary hypertension through a mechanism involving hyperuricemia. |
| PubMedID- 21644841 | Methods: metabolic syndrome patients with hypertension (n=28) and a control group (n=20) were given atenolol (50 mg/day) for 4 weeks. |
| PubMedID- 23675242 | Fibrinogen levels are strongly correlated with traditional vascular risk factors, including age, physical inactivity, hypertension, smoking, and features of the insulin resistance syndrome. |
| PubMedID- 24958506 | Role of nitric oxide synthase uncoupling at rostral ventrolateral medulla in redox-sensitive hypertension associated with metabolic syndrome. |
| PubMedID- 23517220 | Abpm should be a priority for persons likely to have a blunted nighttime bp decline and elevated cvd risk, i.e., those who are elderly and obese, those with secondary or resistant hypertension, and those diagnosed with diabetes, ckd, metabolic syndrome, and sleep disorders. |
| PubMedID- 24122442 | Pm should be a priority for personslikely to have a blunted nighttime bp decline and elevated cvd risk, i.e., those who are elderly and obese, those with secondary or resistant hypertension, andthose diagnosed with diabetes, ckd, metabolic syndrome, and sleep disorders. |
| PubMedID- 24678944 | Sympathoexcitation and oxidative stress in the brain have pivotal roles in hypertension with metabolic syndrome (mets). |
| PubMedID- 20016031 | Although recent evidence underscores the role of heme-oxygenase (ho) in diabetes, its effects on insulin sensitivity and glucose metabolism in spontaneously hypertensive rat (shr), a model of essential hypertension with characteristics of metabolic syndrome including insulin resistance/impaired glucose metabolism remains largely unclear. |
| PubMedID- 21623724 | [possibilities of the use of moxonidine in the treatment of arterial hypertension in patients with metabolic syndrome and diabetes]. |
| PubMedID- 20233452 | All the risk factors in our study, including overweight (obesity), dyslipidaemias and hypertension are components of the metabolic syndrome and insulin resistance. |
| PubMedID- 25916862 | Renin-angiotensin-aldosterone system (raas) inhibition with an ace or an arb and treatment with calcium channel blockers appears safe and well tolerated in obesity-related hypertension and in patients with metabolic syndrome. |
| PubMedID- 20213371 | In addition, in refractory hypertension and in patients with metabolic syndrome aldosterone seems to play an important role. |
| PubMedID- 24729809 | All parameters of metabolic syndrome with resolving/improving t2dm, hypertension, joint disease, depressive disorders or sleep apnoea are normalized or markedly improved after lsg. |
| PubMedID- 26504474 | Increased fructose ingestion has been linked to obesity, hyperglycemia, dyslipidemia, and hypertension associated with metabolic syndrome. |
| PubMedID- 20556204 | Ldl-c, triglycerides, uric acid, bmi, serum glucose, metabolic syndrome, smoking, hypertension and prehypertension),[46, 47, 49] some of which are commonly found in patients with pbc. |
| PubMedID- 24658007 | Hsd11b1 enzymatic activities are thought to be involved in obesity, hypertension, and other components of the metabolic syndrome. |
| PubMedID- 22754464 | In the course of months or years, ir is followed by the increase in β-cell insulin secretion and by several complications known as the insulin resistance syndrome, which is associated with dyslipidemia, hypertension, hyperglycemia and cardiovascular disease [4]. |
| PubMedID- 26064845 | In fact, insulin resistance, dyslipidemia, obesity and hypertension, each of these variables of metabolic syndrome gets influenced by the serum uric acid level. |
| PubMedID- 22350229 | Obesity, dyslipidemia, type 2 diabetes, hypertension, and other components of metabolic syndrome actively correlate with development of nonalcoholic fatty liver disease (nafld) and hepatic insulin resistance and inadequate diabetes resolution after rygb [26]. |
| PubMedID- 24474950 | Sixty-six self-identified african-american subjects with stage 1 and 2 hypertension and characteristics of the cardiometabolic syndrome were treated with amlodipine/olmesartan (a/o) versus losartan/hydrochlorothiazide (l/h) for 20 weeks in an open-label, active comparator fashion. |
| PubMedID- 25993638 | Increased cardiovascular mortality in subjects with metabolic syndrome is largely attributable to diabetes and hypertension in 159,971 korean adults. |
| PubMedID- 21390196 | Fifty nine had isolated metabolic syndrome (group a) and 97 had metabolic syndrome with hypertension and/or diabetes (group b). |
| PubMedID- 24386118 | Our present analyses, however, showed no association between ser23 c with bmi, dyslipidemia, or hypertension, three correlates of metabolic syndrome. |
| PubMedID- 21925996 | The renin-angiotensin system (ras) is a common link between hypertension and comorbidities of obesity and metabolic syndrome (mets). |
| PubMedID- 22555437 | Comprehensive studies, ranging from in vitro, in vivo, preclinical, to human, all suggest that attenuation of gc signaling, through 11β-hsd1 inhibition in metabolically important tissue such as the liver, is a therapeutically achievable strategy to ameliorate the glucose intolerance, obesity, fatty liver, and hypertension associated with metabolic syndrome. |
| PubMedID- 23835112 | Sixty-six african-american subjects with stage 1 and 2 hypertension and characteristics of the metabolic syndrome were treated in open-label, active comparator fashion for 20 weeks. |
| PubMedID- 22934054 | On the other hand, increased adipose tissue mass is associated with insulin resistance, systemic dyslipidemia, hyperglycemia, hypertension, and components of the metabolic syndrome (dandona et al., 2005; despres, 2006). |
| PubMedID- 24209601 | In multivariable analysis, female gender, age > 65 years, smoke, non-hypertension, duration of diabetes > 10 years, metabolic syndrome, egfr < 90 ml/min/1.73 m2, and ga > 18.3% were independently determinants for low collateralization in diabetic patients. |
| PubMedID- 25245490 | However, it appears to be a risk factor for early onset hypertension in metabolic syndrome. |
| PubMedID- 24798707 | metabolic syndrome induces hypertension and commonly results in renal damage. |
| PubMedID- 24485020 | Insulin resistance and hypertension are the components of metabolic syndrome and often coexist [4]. |
| PubMedID- 22808030 | Furthermore, microparticles promote endothelial dysfunction in metabolic syndrome patients with moderate hypertension [8]. |
| PubMedID- 25354240 | Thus, preserved stimulation of proximal tubule transport through the insulin/irs2/pi3-k pathway may play an important role in the pathogenesis of hypertension associated with metabolic syndrome. |
| PubMedID- 25508240 | Material and methods: we conducted an 8-week open prospective study on 36 patients with essential stage ii hypertension associated with metabolic syndrome. |
| PubMedID- 23835856 | Conclusions: in this study, children's hypertension was a component of the metabolic syndrome, but uric acid and hscrp levels were not contributive. |
| PubMedID- 24410986 | All components of metabolic syndrome, including hypertension [4,5], insulin resistance(ir) [6,7], and low hdl-c, together with high levels of tg [8,9] are frequent in patients with osas. |
| PubMedID- 23849214 | Abpm should be a priority for persons likely to have a blunted nighttime bp decline and elevated cvd risk, i.e., those who are elderly and obese, those with secondary or resistant hypertension, and those diagnosed with diabetes, ckd, metabolic syndrome, and sleep disorders. |
| PubMedID- 22866890 | The hfcd-fed sd rats developed a severe metabolic syndrome consistent with hypertension and hypercholesterolemia[18,19]. |
| PubMedID- 25760026 | Metabolic detuning has been reported to be involved in obesity, dyslipidemia, diabetesmellitus, and hypertension, all of which characterize metabolic syndrome and are closelyassociated with insulin resistance. |
| PubMedID- 22294071 | Exploratory studies in patients with resistant hypertension and a variety of comorbidities, including insulin resistance/metabolic syndrome, obstructive sleep apnea and the polycystic ovary syndrome, have shown benefit of renal denervation in attenuating the severity of the comorbid conditions, as well as reducing bp. |