eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | hepatitis c |
| Comorbidity | |cirrhosis |
| Sentences | 155 |
| PubMedID- 21507271 | Hepatocellular carcinoma and hepatic cirrhosis are consequences of chronic hepatitis c. the mean infection time to onset of cirrhosis is approximately 30 years, but cirrhosis may occur within a range of 10-50 years [20]. |
| PubMedID- 25270208 | Conclusion: from the stage of chronic infection to decompensated cirrhosis, patients with hepatitis c were found with the decreased numbers of cd4(+)t, cd8(+) t and nk lymphocytes, and the increased proportion of b lymphocyte and cd4/cd8 ratio. |
| PubMedID- 25057737 | From 1996 to 2006, the prevalence of cirrhosis among veterans with chronic hepatitis c infection rose from 9 to 18.5%, and the prevalence of hcc rose from 0.07 to 1.3%. |
| PubMedID- 22536498 | Thrombocytopenia and reversed albumin/globulin ratio can be detected in cases with progressive liver cirrhosis in patients with hepatitis c. also, serological markers correlated with stages of liver fibrosis can be used with indices obtained from routine blood tests to determine the function of the liver (e.g., apri (aspartate aminotransferase [ast]-to-platelet ratio index) and fib-4 (age, ast, platelets, and alt level)). |
| PubMedID- 24308724 | Von willebrand factor as a new marker for non-invasive assessment of liver fibrosis and cirrhosis in patients with chronic hepatitis c. |
| PubMedID- 24973874 | It was concluded that the increase of cu and fe content in human body seems to contribute to the development of cirrhosis in patients with viral hepatitis c. |
| PubMedID- 22087154 | This study included 175 consecutive patients with liver cirrhosis due to hepatitis c virus. |
| PubMedID- 23751845 | Background and aim: data on outcome of patients after liver transplantation (lt) for cirrhosis due to hepatitis c virus (hcv+) alcohol are limited. |
| PubMedID- 23317427 | Methods: all consecutive japanese patients with hepatic cirrhosis due to hepatitis c who had undergone elective splenectomy in kyushu university hospital between january 2008 and december 2009 were included in this retrospective study. |
| PubMedID- 26196278 | Statin use and the risk of cirrhosis development in patients with hepatitis c virus infection. |
| PubMedID- 20422871 | A 45-year-old man under treatment for liver cirrhosis (lc) due to chronic hepatitis c and hemophilia a was seen in our emergency room because of a 10-kg weight gain in the previous week due to ascites. |
| PubMedID- 21253791 | Curing hepatitis c infection in patients with cirrhosis through treatment with peginterferon and ribavirin reduces the risk of developing hepatocellular carcinoma. |
| PubMedID- 23300494 | Patients and methods: ninety patients were enrolled: 30 cases of chronic hepatitis c (chc) without cirrhosis, 30 cases of chc with liver cirrhosis, and 30 cases of hcc and hepatitis v virus (hcv) infection. |
| PubMedID- 20497143 | Systematic review: outcome of compensated cirrhosis due to chronic hepatitis c infection. |
| PubMedID- 21182362 | Chronic hepatitis c is associated with cirrhosis, hepatic failure, and death; therefore, treatment is aimed at reducing these complications, as well as improving quality of life and minimizing adverse effects. |
| PubMedID- 20558353 | Conclusions: risk factors for new-onset diabetes after transplantation are older age, obesity, male gender and cirrhosis due to hepatitis c infection. |
| PubMedID- 22087173 | cirrhosis due to chronic hepatitis c virus (hcv) infection is one of the leading indications for liver transplantation (lt) worldwide. |
| PubMedID- 20426802 | Once developed, 30% to 40% of these patients succumb a liver-related death over a 10-year period [51,52], a mortality rate similar to[53,54] or worse than cirrhosis associated with hepatitis c. nash-associated cirrhosis can also develop into into a subacute liver failure, or progress to hepatocellular cancer [55], as well as reoccur after liver transplantation. |
| PubMedID- 21526140 | Transient elastography has also been demonstrated to be a reliable tool for assessing fibrosis and cirrhosis mainly in patients with chronic hepatitis c (chc) [5, 6]. |
| PubMedID- 26237567 | A 59 year-old woman with liver cirrhosis due to hepatitis c, complicated by refractory hepatic hydrothorax was treated with a tips (transjugular intrahepatic portosystemic shunt) procedure. |
| PubMedID- 26486859 | Impact of liver cirrhosis due to chronic hepatitis c viral infection on the outcome of ovarian cancer: a prospective study. |
| PubMedID- 20811639 | For the cirrhosis group, patients with hepatitis c and biopsy-proven cirrhosis were enrolled. |
| PubMedID- 22484974 | [invasive pulmonary aspergillosis and esophageal candidiasis in a patient with decompensated liver cirrhosis due to chronic hepatitis c and alcohol]. |
| PubMedID- 23182962 | Using fluorescence in situ hybridization (fish) analysis, we examined the replication mode of the centromere region (homologous counterpart) and the aneuploidy level of chromosome 17 in the interphase nuclei of phytohaemagglutinin (pha)-stimulated peripheral blood lymphocytes from (1) patients with hepatocellular carcinoma (hcc); (2) patients with liver cirrhosis (lc) due to hepatitis c viral infection who are individuals at a higher increased risk for hcc; and (3) healthy control participants. |
| PubMedID- 22219600 | In contrast, 5 hepatitis c patients with cirrhosis showed much decreased sh2a levels (50 +/- 9 ng/ml). |
| PubMedID- 26176835 | cirrhosis due to hepatitis c infection is the leading indication for liver transplantation worldwide. |
| PubMedID- 21184757 | Increasing prevalence of hcc and cirrhosis in patients with chronic hepatitis c virus infection. |
| PubMedID- 26513826 | [hope for cirrhosis patients with genotype 1 hepatitis c virus who failed the previous treatment]. |
| PubMedID- 25187808 | In conclusion, the combination of fuzheng huayu capsule with pegasys inhibited liver fibrosis and cell apoptosis, and may be a novel therapeutic strategy for the treatment of patients with compensated cirrhosis due to hepatitis c. |
| PubMedID- 23170044 | A total of 62 japanese patients with chronic hepatitis (ch) or liver cirrhosis (lc) attributable to persistent hepatitis c virus infection and who were examined at nihon university itabashi hospital from september 1999 through january 2001, gave informed consent to their participation in this study. |
| PubMedID- 24766091 | Background & aims: chronic hepatitis c may be associated with cirrhosis, liver failure and hepatocellular carcinoma. |
| PubMedID- 20964825 | Tlr4 was identified as one of seven genes associated with increased risk of developing cirrhosis in patients with chronic hepatitis c [72,121]. |
| PubMedID- 21777434 | (1998), this test cannot predict significant cirrhosis in patients with chronic hepatitis c [30]. |
| PubMedID- 25374720 | In this paper, we report on a 48-year-old patient with pleuropulmonary nocardiosis and cirrhosis due to chronic hepatitis c virus infection treated with triple antiviral treatment complicated by prolonged neutropenia. |
| PubMedID- 19959940 | A case of compensated liver cirrhosis with hepatitis c virus of genotype 1b and high viral load in whom sustained virological response was achieved by 2-year administration of very low-dose recombinant interferon alpha-2b. |
| PubMedID- 23139898 | In fact, the proportion of chronic hepatitis c patients with cirrhosis is expected to reach 25% in 2010 and 45% in 2030 (davis et al. |
| PubMedID- 20818236 | Background: excessive alcohol consumption is associated with an increased risk for fibrosis progression and cirrhosis in patients with chronic hepatitis c virus (hcv) infection. |
| PubMedID- 23222845 | Despite a generally asymptomatic course of hcv infection in children with mild histological changes in the liver, chronic hepatitis c may lead to liver fibrosis, cirrhosis, and even hcc in children and adolescents [16,17]. |
| PubMedID- 24027085 | However, meanwhile, half of those patients have died of end-stage liver cirrhosis due to hepatitis c virus (hcv) with liver cirrhosis and early occurrence of hepatocellular carcinoma. |
| PubMedID- 24281168 | Plasma ykl-40 predict cirrhosis (ishak 5/6) in patients with chronic hepatitis c, but was not included in the final three-variable model consisting of serum hyaluronan, tissue inhibitor of metalloprotinases (timp)-1 and platelet count [171,172]. |
| PubMedID- 25074044 | Methods: we describe a patient with decompensated cirrhosis because of severe recurrent hepatitis c, who had a retransplant following treatment with a combination of sofosbuvir and riba virin that started during the waiting time and was carried over during both the transplant and post-transplant phases for an overall period of 24 weeks. |
| PubMedID- 21410221 | Using this approach we show that the beta chains of complement c3 and c4 decrease in serum from hepatitis c patients with cirrhosis, a change not observed previously by 2-de. |
| PubMedID- 21360032 | The average recoveries +/- rsd for the healthy subjects, cirrhosis of chronic hepatitis c and b, and hcc serum samples were 102.6 +/- 1.01%, 101.5 +/- 0.95%, and 100.1 +/- 1.1%, respectively. |
| PubMedID- 25993176 | The vast majority of hcc cases occur in the setting of liver cirrhosis, mainly due to chronic hepatitis c (hcv) or hepatitis b (hbv) viral infections, alcohol consumption, and nonalcoholic fatty liver disease. |
| PubMedID- 24378262 | Anti-hbc positivity was associated with histological cirrhosis in patients with chronic hepatitis c. |
| PubMedID- 24919730 | A patient with local recurrence of hepatocellular carcinoma 36 months after liver transplant for multifocal hepatocellular carcinoma and cirrhosis due to hepatitis c was successfully treated with laparoscopic microwave ablation without any postoperative complications. |
| PubMedID- 21330908 | The natural history of liver cirrhosis in hiv-hepatitis c virus-coinfected patients. |
| PubMedID- 21920398 | Kir genes and their human leukocyte antigen ligands in the progression to cirrhosis in patients with chronic hepatitis c. |
| PubMedID- 21687605 | Compared the diagnostic accuracy of using 13c-mbt with several noninvasive tests like the apri, aar, and fibroindex and found that the 13c-mbt was more reliable in predicting advanced fibrosis and cirrhosis in patients with chronic hepatitis c [22]. |
| PubMedID- 21079746 | Chronic hepatitis c (chc) may lead to liver cirrhosis and hepatocellular carcinoma. |