eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | hemorrhagic fever with renal syndrome |
| Comorbidity | |hemorrhagic fever with renal syndrome |
| Sentences | 116 |
| PubMedID- 24674957 | These rna viruses of the family bunyaviridae are the etiologic agents of hemorrhagic fever with renal syndrome (hfrs) in europe and asia, and hantavirus cardiopulmonary syndrome (hcps), in the americas [1,2]. |
| PubMedID- 22934002 | The relationship between the rodent population density, the hantavirus prevalence in the rodent population, and the number of human hantavirus cases, including the hemorrhagic fever with renal syndrome (hfrs) cases in eurasia, has been suggested worldwide (tersago et al., 2011a). |
| PubMedID- 24732259 | Currently available vaccines produced on primary mammalian cells protect against hemorrhagic fever with renal syndrome and japanese encephalitis (hantavax, korea green cross, and je-vax, sanofi pasteur/biken, both propagated in mouse brain, and sa 14-14-2 je, chengdu vaccine plant, derived from primary hamster kidney cells). |
| PubMedID- 26437779 | These results correspond to observations on other viral hemorrhagic fevers (vhfs) such as hemorrhagic fever with renal syndrome (hfrs), severe fever with thrombocytopenia (sfts), crimean-congo hemorrhagic fever (cchf) and ebola virus disease (evd) [33–38, 41]. |
| PubMedID- 24133366 | Hantavirus infection induces 2 different diseases, hemorrhagic fever with renal syndrome (hfrs) and hantavirus pulmonary syndrome (hps), mainly in korea, far east russia, and china and in the united states, respectively (1, 2). |
| PubMedID- 24877080 | However, both anaplasmosis and ehrlichiosis are often underrecognized in china because epidemiological, ecological, clinical, and microbiological information about these two bacteria is very limited, and both diseases are often misdiagnosed due to their clinical manifestation's similarity to hemorrhagic fever with renal syndrome (hfrs) [14–16]. |
| PubMedID- 25888018 | hemorrhagic fever with renal syndrome (hfrs) mainly caused by seoul, puumala and dobrava viruses; nephropathia epidemica, a mild form of hfrs caused by puumala virus; and hantavirus cardiopulmonary syndrome, which may be caused by andes virus and sin nombre virus. |
| PubMedID- 22932394 | Human hantavirus disease is manifested as hemorrhagic fever with renal syndrome (hfrs) in asia, europe, and most probably africa (1). |
| PubMedID- 25836633 | Hantaan virus (htnv), the prototype of hantavirus genus, is a rodent-borne pathogen that causes human hemorrhagic fever with renal syndrome, with mortality rate of approximately 15% in asia. |
| PubMedID- 21838931 | Puumala hantavirus (puuv) causes a hemorrhagic fever with renal syndrome (hfrs) also called nephropathia epidemica (ne). |
| PubMedID- 24505382 | Autoregressive integrated moving average (arima) models have been widely used for epidemic time series forecasting including the hemorrhagic fever with renal syndrome [6], [7], dengue fever [8], [9], and tuberculosis [10]. |
| PubMedID- 21709630 | hemorrhagic fever with renal syndrome was excluded. |
| PubMedID- 21264354 | Hantavirus can cause two kinds of human illnesses, hantavirus cardiopulmonary syndrome (hcps) and hemorrhagic fever with renal syndrome (hfrs). |
| PubMedID- 22523590 | Puumala hantavirus (puuv) infection, also known as nephropathia epidemica (ne), is the most common cause of hemorrhagic fever with renal syndrome (hfrs) in europe [1]. |
| PubMedID- 22443897 | In addition, changing epidemiology has been observed for some viral infections, such as hemorrhagic fever with renal syndrome after the introduction of the vaccine in korea [29], and acquired immunodeficiency syndrome (aids) after the introduction of antivirals [30]. |
| PubMedID- 21234633 | The present paradigm is that hantaviruses in the americas cause hantavirus pulmonary syndrome (hps), while hemorrhagic fever with renal syndrome (hfrs) is caused by hantaviruses present in eurasia [1–3]. |
| PubMedID- 22924041 | Hantaviruses are present worldwide and responsible for two diseases: hemorrhagic fever with renal syndrome (hfrs) and hantavirus pulmonary syndrome (hps). |
| PubMedID- 24638203 | Some members of this genus are not pathogenic to humans, but others produce two distinct illnesses: (i) those found in asia and europe (old world hantavirus) cause hemorrhagic fever with renal syndrome (hfrs), which have a lethality approaching 12%, or epidemic nephropathy (en) (a less severe form of the previous disease), with an approximate lethality of 1%; (ii) the viruses circulating in the americas (new world hantaviruses) generate a severe respiratory disease called hantavirus pulmonary syndrome (hps), associated with a lethality between 10% and 50% depending of the virus genotype [2,3]. |
| PubMedID- 24481251 | hemorrhagic fever with renal syndrome (hfrs) is caused by hantaviruses in the asia-pacific area. |
| PubMedID- 22545121 | Hantaviruses (bunyaviridae family) are rodent-borne emerging viruses which cause two significant human diseases; hemorrhagic fever with renal syndrome (hfrs) in asia and europe, and hantavirus cardiopulmonary syndrome in the americas. |
| PubMedID- 25913899 | In the field of public health, arima models are used to describe and forecastthe incidence of infectious diseases, such as campylobacteriosis [3], severe acute respiratory syndrome (sars) [11], hemorrhagic fever with renal syndrome (hfrs) [18], cholera [2], onchocerciasis[17], influenza [25], malaria [31] and dengue fever [4], and even the number of patients visiting emergencydepartments [23, 26]. |
| PubMedID- 24377763 | The genus hantavirus, family bunyaviridae, contains human pathogenic viruses that cause hemorrhagic fever with renal syndrome (hfrs) and hantavirus cardiopulmonary syndrome (1). |
| PubMedID- 22187258 | Toxic epidermal necrolysis may be considered as a possible complication of hemorrhagic fever with renal syndrome vaccination. |
| PubMedID- 21122229 | Hantavirus disease has 2 recognized clinical forms, hemorrhagic fever with renal syndrome and hantavirus pulmonary syndrome (hps) (2). |
| PubMedID- 24152599 | Used circular windows no more than 20% to identify hemorrhagic fever with renal syndrome clusters and smaller circular windows no more than 10% to identify possible subclusters for more efficient resource allocation for preventing hemorrhagic fever with renal syndrome [41]. |
| PubMedID- 20012277 | 2002), cause hemorrhagic fever with renal syndrome (hfrs), whereas, new world hantaviruses, such as sin nombre and andes viruses (schmaljohn and hjelle 1997; meyer and schmaljohn 2000), are the causative pathogen of hantavirus pulmonary syndrome (hps). |
| PubMedID- 21867563 | hemorrhagic fever with renal syndrome (hfrs) is a rodent-borne disease caused by hantavirus, with characteristics of fever, hemorrhage, kidney damage, and hypotension [1-3]. |
| PubMedID- 22506017 | When transmitted to humans, hantaviruses cause hemorrhagic fever with renal syndrome (hfrs) or hantavirus (cardio) pulmonary syndrome (hps) [3], [4]. |
| PubMedID- 22615877 | Its ability to augment th1-associated antibody responses was further demonstrated in studies using three commercial inactivated vaccines against hemorrhagic fever with renal syndrome, flu and rabies [29]. |
| PubMedID- 23171649 | Members of both genera can cause life-threatening diseases in humans: arenaviruses cause hemorrhagic fevers in the americas and africa, and hantaviruses cause hemorrhagic fever with renal syndrome in asia and europe and hantavirus cardiopulmonary syndrome in the americas. |
| PubMedID- 24236203 | Ribavirin is reported to be effective for treating cchf infections and hemorrhagic fever with renal syndrome [7,38]. |
| PubMedID- 24576845 | In humans, hantaviruses are known to cause a broad range of clinical disease, mainly affecting the renal tract: hemorrhagic fever with renal syndrome (hfrs), with its milder form, nephropathia epidemica (ne), or the respiratory tract: hantavirus cardiopulmonary syndrome (hcps) caused by certain old and new world hantaviruses, respectively [10,21,40]. |
| PubMedID- 24714064 | Unlike in rodents, hantavirus infection leads to two different forms of severe febrile disease in humans, hemorrhagic fever with renal syndrome (hfrs) [3] and hantavirus pulmonary syndrome (hps) [4]. |
| PubMedID- 22811711 | Hantaviruses predominantly infect microvascular endothelial cells (ecs), which line vessels and nonlytically cause two vascular diseases: hemorrhagic fever with renal syndrome (hfrs) and hantavirus pulmonary syndrome (hps) [1–14]. |
| PubMedID- 22854669 | In addition to these fda-licensed vaccines, several vaccines; for example, against malaria, tularemia, dengue, hiv-aids, chikungunya, rift valley fever, argentinian hemorrhagic fever, and hemorrhagic fever with renal syndrome (hfrs), have been developed and tested in clinical studies by the military but have not yet been, or never will be, licensed. |
| PubMedID- 21569520 | Two major severe pathologies associated to hantaviruses have been reported: hemorrhagic fever with renal syndrome (hfrs) in the eurasia and hantavirus cardiopulmonary syndrome (hcps) in the americas. |
| PubMedID- 20875284 | Hantaviruses cause 2 severe emerging zoonotic diseases: hemorrhagic fever with renal syndrome (hfrs) in eurasia and hantavirus cardiopulmonary syndrome (hcps) in the americas. |
| PubMedID- 24587107 | Abbreviations: hf, hemorrhagic fever; hyshf, huaiyangshan hemorrhagic fever; hfrs, hemorrhagic fever with renal syndrome; wbc, white blood cell; neut, neutrophil; lymph, lymphocyte; mono, monocyte; eos, eosinophil; rbc, red blood cell; hgb, hemoglobin; plt, platelet; ldh, lactate dehydrogenase; ck, creations kinase; ck-mb, creative kinase isoenzyme mb; hbdh, hydroxyhutyrate dehydrogenase; na, sodium; cl, chlorine; ca, calcium; bun, blood urea nitrogen; crea, creatinine; urca, uric acid; pt, prothrombin time; tt, thrombin time; alt, alanine aminotransferase; ast, aspartate aminotransferase; tbil, total bilirubin; dbil, direct bilirubin; alb, albumin; glo, globulin; ggt, gamma-glutamyl transferase; alp, alkaline phosphatase; tba, total bile acids; ada, adenosine deaminase. |
| PubMedID- 24584027 | Given the worldwide threat of hantaviruses and an estimated 200,000 new cases of both hemorrhagic fever with renal syndrome (hfrs) and hps appearing each year [2], evaluating outreach efforts will help enable public health officials to design efficient and effective programs in the future. |
| PubMedID- 24402305 | Hps: hantavirus pulmonary syndrome; hfrs: hemorrhagic fever with renal syndrome; * according to [20,45,55]; ** according to [106,143,144]; *** according to [139,141]; **** according to [1,141]; § according to [145]. |
| PubMedID- 22709722 | hemorrhagic fever with renal syndrome (hfrs) is caused by infection with hantaviruses. |
| PubMedID- 21303497 | It is the agent of a mild form of hemorrhagic fever with renal syndrome called nephropathia epidemica (ne). |
| PubMedID- 24505421 | Hantaviruses cause two febrile illnesses in humans, namely hemorrhagic fever with renal syndrome (hfrs) in the old world, and hantavirus pulmonary syndrome (hps) in the new world [1], [3]. |
| PubMedID- 24416167 | Arima models can eliminate seasonal patterns and are widely applied in predictions for epidemics like hemorrhagic fever with renal syndrome (hfrs), influenza, malaria, etc [8], [9]. |
| PubMedID- 21857951 | In addition, scrub typhus-like diseases, including murine typhus, leptospirosis, hemorrhagic fever with renal syndrome, and systemic lupus erythematosus were excluded based on laboratory tests and clinical features. |
| PubMedID- 20862319 | Several bunyaviruses are important or emerging human or plant pathogens including la crosse orthobunyavirus (childhood encephalitis), hantaan virus (hemorrhagic fever with renal syndrome), rift valley fever phlebovirus, tomato spotted wilt tospovirus and crimean-congo (hemorrhagic fever) nairovirus. |
| PubMedID- 20096099 | This group of viruses includes the etiological agents of hemorrhagic fever with renal syndrome (hfrs), largely seen in europe and asia, and hantaviruses causing (cardio) pulmonary syndrome (hcps) in the americas. |
| PubMedID- 25912713 | Recently, the more inclusive name hantavirus disease has been proposed to define the clinical manifestation of infection instead of the traditionally used hemorrhagic fever with renal syndrome (hfrs) and hantavirus cardiopulmonary syndrome (hcps) due to better understanding of the diversity of clinically overlapping manifestations beyond two distinct syndromes and the occurrence of mild or asymptomatic infection that may go underdiagnosed [5,6]. |
| PubMedID- 25874194 | In europe, puumala virus (puuv), the most prevalent hantavirus in western and northern europe (1), is responsible for hemorrhagic fever with renal syndrome, often called nephropathia epidemica (ne) in humans (2, 3). |
| PubMedID- 24209605 | The causative agents of hemorrhagic fever with renal syndrome in central europe are dobrava-belgrade virus and puuv (4). |