eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | c syndrome |
| Comorbidity | |diabetes |
| Sentences | 163 |
| PubMedID- 21448316 | The risk of having metabolic syndrome for women with type 2 diabetes mellitus was higher by the idf criteria than the ncep-atp iii criteria. |
| PubMedID- 22113483 | Sensitivity analyses were undertaken using the revised ncep atp iii definition (glucose cut point >5.6mmol/l) and the international diabetes federation (idf) definitions of metabolic syndrome (zimmet et al., 2005). |
| PubMedID- 22144985 | This in utero programming seems to create a kind of “metabolic memory,” since physiological anomalies of gestational period are responsible for the onset of diseases in offspring at adulthood, such as type 2 diabetes and obesity associated with metabolic syndrome. |
| PubMedID- 20823099 | Of significance in the zucker diabetic fat rat, a model of type 2 diabetes associated with the metabolic syndrome, ebselen improved endothelial dysfunction and renal insufficiency (21,22). |
| PubMedID- 20587704 | Research design and methods: the study involved a group of 242 metabolic syndrome patients with or without pre-diabetes and randomized to atorvastatin, fenofibrate, or placebo. |
| PubMedID- 23127161 | Lower adiponectin levels were observed in participants with the following characteristics: male, former smoking, hypertension, diabetes, homeostasis model assessment of insulin resistance (homa-ir), metabolic syndrome, moderate alcohol use, elevated waist circumference, bmi, estimated glomerular filtration rate (egfr), triglycerides, low-density lipoprotein cholesterol (ldl-c), lower high-density lipoprotein cholesterol (hdl-c), and younger age. |
| PubMedID- 24103901 | Prevention of type 2 diabetes in subjects with prediabetes and metabolic syndrome treated with phentermine and topiramate extended release. |
| PubMedID- 24072533 | In vitro studies using human aortic endothelial cells showed that ebselen abrogates h2o2‐induced increases in p‐ikk, p‐jnk, tumor necrosis factor–α, and nox2.24,46 in zucker diabetic fat rats, a model of type 2 diabetes associated with metabolic syndrome, ebselen prevented premature endothelial cell senescence and improved endothelial dysfunction (improved acetylcholine response).23 cellular antioxidant enzymes such as glutathione peroxidase 1 and superoxide dismutase have a central role in the control of reactive oxygen species. |
| PubMedID- 24554764 | Kdm3a knockdown leads to immotile round-headed spermatozoa (globozoospermia) and metabolic syndrome associated with obesity and diabetes (okada et al., 2007; inagaki et al., 2009; tateishi et al., 2009; liu et al., 2010) through the regulation of genes involved in histone replacement during spermatogenesis and regulation of gene expression during adipogenesis. |
| PubMedID- 24411997 | However, few studies are available on the impact of sleep duration on metabolic syndrome in patients with diabetes, who were at high risk for cardiovascular diseases (cvd). |
| PubMedID- 21525475 | In a subanalysis of allhat, chlorthalidone was superior to the other agents in preventing hf in participants with the metabolic syndrome and in patients with diabetes (18). |
| PubMedID- 20012885 | This study determines the prediction of low-risk lifestyle on type 2 diabetes in those with and without metabolic syndrome in a pooled sample of two representative finnish cohorts, collected in 1978-1980 and 2000-2001. |
| PubMedID- 21472664 | Comparison of efficacy of pitavastatin and colestimide in japanese patients with diabetes mellitus complicated by hyperlipidemia and metabolic syndrome. |
| PubMedID- 20028945 | Changes in adipose tissue distribution could accompany significant improvements in the components of the metabolic syndrome in individuals with type 2 diabetes (35–36); however, we did not find that the relationships specifically between improvements in the adipose tissue distribution and improvements in the peripheral insulin sensitivity were independent of the change in overall weight and adipose tissue mass. |
| PubMedID- 25258634 | Background: diabetes mellitus, one of the leading metabolic syndromes, accounts for highest morbidity and mortality worldwide. |
| PubMedID- 20376319 | Subjects: thirty-five patients undergoing bariatric surgery were classified as mho (n = 15) or metabolically unhealthy obese (muo, n = 20) according to cut-off points adapted from the international diabetes federation definition of the metabolic syndrome. |
| PubMedID- 22187640 | In humans, a daily intake of at least 5 g of soluble fiber, particularly from whole-grain foods and fruits, reduced the presence of metabolic syndrome in patients with type 2 diabetes by 54% [65]. |
| PubMedID- 20626665 | Resting heart rate and metabolic syndrome in patients with diabetes and coronary artery disease in bypass angioplasty revascularization investigation 2 diabetes (bari 2d) trial. |
| PubMedID- 22474593 | At present, little data exist about incidence and the risk factors associated with metabolic syndrome (mets) in patients with type 2 diabetes mellitus (t2dm). |
| PubMedID- 23484675 | Applying laws of biology to diabetes with emphasis on metabolic syndrome. |
| PubMedID- 25993638 | Increased cardiovascular mortality in subjects with metabolic syndrome is largely attributable to diabetes and hypertension in 159,971 korean adults. |
| PubMedID- 23728331 | Type 2 diabetes mellitus with metabolic syndrome developed at 30 weeks of age, and the body weights and plasma insulin levels of oletf rats at 60 weeks of age were lower than those of normal rats. |
| PubMedID- 20653460 | In this paper the relationship between depression and the metabolic syndrome among patients with type 1 diabetes was evaluated. |
| PubMedID- 25729439 | Furthermore, the cardia study showed a direct association between childbearing and incidence of metabolic syndrome among women with gestational diabetes mellitus but not among women without it [8]. |
| PubMedID- 21409896 | The objective of the study was to observe the frequency of metabolic syndrome (mets) in patients with type 2 diabetes mellitus and study the relationship of insulin resistance with the metabolic syndrome and its different clinical parameters. |
| PubMedID- 24843651 | In patients with type 2 diabetes, the prevalence of metabolic syndrome‐oriented type 2 diabetes, which is characterized by insulin resistance16, increases as much as 45.9% in males and 28.0% in females17. |
| PubMedID- 24594198 | Background: the incidence of macrovascular complications and morbidities associated to metabolic syndrome are increasing in patients with type 1 diabetes mellitus (t1dm). |
| PubMedID- 20813084 | Aim of the study was the assessment of overweight, obesity and other elements of the metabolic syndrome in children with type 1 diabetes mellitus. |
| PubMedID- 24348536 | Pancreatic fat may be a marker of metabolic syndrome and is associated with diabetes, independent of other risk factors [10, 32, 44]. |
| PubMedID- 21089455 | [cardiac autonomous neuropathy and metabolic syndrome in patients with type 2 diabetes mellitus]. |
| PubMedID- 19690575 | Snp276g>t polymorphism in the adiponectin gene is associated with metabolic syndrome in patients with type ii diabetes mellitus in korea. |
| PubMedID- 23978069 | Hypertension, obesity, hyperlipidemia, and diabetes, the main manifestations of metabolic syndrome, do not always present simultaneously, while in obese patients, the presence of at least three of these manifestations can lead to crp elevation [30]. |
| PubMedID- 20178560 | Patients with chc may develop hepatic steatosis as a consequence of concomitant metabolic syndrome, possibly associated with type 2 diabetes, obesity or increased body mass index (bmi). |
| PubMedID- 24741576 | In the literature, it has been described that plasma il-6 levels are associated with increased cv risk and observed in sle patients with metabolic syndrome [53] and in patients with type 2 diabetes [44, 54]. |
| PubMedID- 23949560 | The insulin resistance milieu of type 2 diabetes is closely associated with metabolic syndrome—a clustering of risk factors that includes hypertension, abdominal adiposity, dyslipidemia, and inflammation. |
| PubMedID- 25954754 | This also means that membrane transporters, including ion channels and transporters, are very important therapeutic targets in several diseases such as cardiovascular disorders, hypertension, dementia, metabolic syndrome associated with diabetes mellitus, and cancer. |
| PubMedID- 21145931 | These processes are important in diabetes and other facets of the metabolic syndrome, which represents a considerable increasing health burden. |
| PubMedID- 21591574 | Metabolic syndrome with or without diabetes contributes to left ventricular diastolic dysfunction. |
| PubMedID- 22441723 | Background: several genetic syndromes are associated with diabetes mellitus (dm). |
| PubMedID- 22311446 | Metabolic syndrome was defined with the international diabetes federation (idf) criteria. |
| PubMedID- 21272190 | Aim: we examined the effects of the 11beta-hydroxysteroid dehydrogenase type 1 (hsd1) inhibitor, mk-0916, on the multiple components of the metabolic syndrome (mets) in patients with type 2 diabetes (t2dm) and mets. |
| PubMedID- 21562645 | (1,2) type 2 (non-insulin-dependent) diabetes is associated with metabolic syndrome and a marked increase in the risk of cardiovascular morbidity and mortality. |
| PubMedID- 22837677 | Type 2 diabetes is associated with the metabolic syndrome that comprises a set of alterations that include glucose intolerance, truncal obesity, hypertension and dyslipidemia [3]. |
| PubMedID- 21446088 | Conclusion: administration of metformin in type 2 diabetes with metabolic syndrome decreased cardiovascular risk factors by reducing glycemia, triglycerides, bmi, central obesity and insulin resistance. |
| PubMedID- 25053801 | Conclusions: the proinflammatory state associated with metabolic syndrome in patients with type 1 diabetes leads to deterioration of glycaemic control and an increase in the required daily dose of insulin. |
| PubMedID- 20864516 | Among the earth study participants with diabetes, the prevalence of the metabolic syndrome was 86.6 (83.7–88.8) with little difference between men and women. |
| PubMedID- 22701848 | [1112] since metformin is useful for management of diabetes cases with metabolic syndrome, which is a risk factor for sleep apnea,[1314] hence, metformin is helpful for preventing sleep apnea. |
| PubMedID- 20629819 | The aim of this study was to compare hemoglobin a(1c) (hba(1c)) and fasting glucose for the diagnosis of diabetes among people with metabolic syndrome and fasting glucose >100 mg/dl (5.5 mmol/l). |
| PubMedID- 24285222 | Metabolic syndrome was vigorously associated with diabetes mellitus and newly diagnosed diabetes mellitus (12.4% vs. |
| PubMedID- 21498915 | Type 2 diabetes mellitus (t2dm) associated with metabolic syndrome (mets) represents a high risk of cardiovascular disease. |