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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease ulcerative colitis
Symptom C0009402|colorectal cancer
Sentences 37
PubMedID- 25981516 Psc is a premalignant condition, associated with higher rates of hepatobiliary and colorectal cancer in patients with ulcerative colitis (uc).
PubMedID- 25649787 A retrospective dutch nationwide population-based analysis found that approximately 20% of colorectal cancer cases in patients with ulcerative colitis presented prior to the recommended initiation of screening colonoscopy 8.
PubMedID- 22610004 Challenges in calculating the risk for colorectal cancer in patients with ulcerative colitis.
PubMedID- 24766737 The pathogenesis of colorectal cancer in patients with ulcerative colitis is triggered by inflammation-dependent mechanisms 4.
PubMedID- 24295648 Unique endoscopic findings of colitis-associated colorectal cancer in a patient with ulcerative colitis and lynch syndrome.
PubMedID- 25823771 It has been more than 40 years since the colonoscopic surveillance program for colorectal cancer (crc) in patients with long-standing ulcerative colitis (uc) was introduced (1).
PubMedID- 25605985 Copy number variations are progressively associated with the pathogenesis of colorectal cancer in ulcerative colitis.
PubMedID- 23867875 Methylated eyes absent 4 (eya4) gene promotor in non-neoplastic mucosa of ulcerative colitis patients with colorectal cancer: evidence for a field effect.
PubMedID- 21404516 colorectal cancer, in patients with ulcerative colitis, is detected in the resected tissue of approximately 5% of patients, according to the literature.
PubMedID- 25834332 Aim: to determine the incidence and risk factors for colorectal cancer (crc) in patients with ulcerative colitis from a low prevalence region for crc.
PubMedID- 22289873 Risk of colorectal cancer in patients with ulcerative colitis: a meta-analysis of population-based cohort studies.
PubMedID- 22156448 Does colorectal cancer in ulcerative colitis patients constitute a risk for chemotherapy refractoriness.
PubMedID- 21425209 Myeloperoxidase immunohistochemistry as a measure of disease activity in ulcerative colitis: association with ulcerative colitis-colorectal cancer, tumor necrosis factor polymorphism and runx3 methylation.
PubMedID- 22292619 The risk of colorectal cancer in ulcerative colitis patients is estimated to be as high as 40%.
PubMedID- 25888857 Avoiding restorative proctocolectomy for colorectal cancer in patients with ulcerative colitis based on preoperative diagnosis involving p53 immunostaining: report of a case.
PubMedID- 21038106 colorectal cancer is one of the complications of ulcerative colitis (uc) and the risk of cancer increases as the duration of the disease becomes longer.
PubMedID- 23435402 Five-year mortality in colorectal cancer patients with ulcerative colitis or crohn's disease: a nationwide population-based cohort study.
PubMedID- 21618350 Background: chronic ulcerative colitis (uc) is associated with an increased colorectal cancer risk which may be secondary to repetitive mucosal injury.
PubMedID- 25347248 colorectal cancer in ulcerative colitis.
PubMedID- 21647200 Although progress has been made in the understanding of inflammation-driven carcinogenesis, markers based on these findings possess insufficient sensitivity or specificity to be usable as reliable biomarkers for risk of colorectal cancer development in patients with ulcerative colitis.
PubMedID- 19906011 The development of colorectal cancer in ulcerative colitis is a function of disease duration, with the risk approaching 14% at 25 years.
PubMedID- 23139655 Surgical procedure for sporadic colorectal cancer in patients with mild ulcerative colitis.
PubMedID- 21466491 How to manage the risk of colorectal cancer in ulcerative colitis.
PubMedID- 21040676 Development of colorectal cancer in ulcerative colitis.
PubMedID- 24262637 Cost-effectiveness analysis of chromoendoscopy for colorectal cancer surveillance in patients with ulcerative colitis.
PubMedID- 26357617 Risk factors for developing cca in psc patients include elevated serum bilirubin, chronic ulcerative colitis with colorectal cancer or dysplasia, variceal bleeding, proctocolectomy, and polymorphisms of the natural killer group 2, member d (nkg2d) gene (encoding a protein involved in nk cell activity).78, 82, 83 the duration of psc may not be a risk factor for the development of cca, which is contrary to the risk factors of neoplasia in inflammatory bowel disease.77 it is suggested that dominant strictures, defined as a common bile duct stenosis with less than 1.5 mm diameter remaining in the common bile duct or a common hepatic duct stenosis close to the bifurcation leaving less than 1.0 mm diameter of the common hepatic duct,84, 85 may serve as primary indicators of concomitant cca.86 it is very challenging to distinguish between benign strictures from psc activity and cca as they can have similar characteristics on imaging.
PubMedID- 25797989 Surveillance colonoscopy (sc) is considered important for the early detection and treatment of colorectal cancer (crc) in patients with ulcerative colitis (uc).
PubMedID- 22552273 Dysplasia and colorectal cancer in a patient with ulcerative colitis and primary sclerosing cholangitis: a case report and a short review of the literature.
PubMedID- 21873166 Clinical course of colorectal cancer in patients with ulcerative colitis.
PubMedID- 20698214 Clinicopathological study of colorectal cancer occurring in patients with ulcerative colitis: results from a single hospital in japan.
PubMedID- 25280558 The risk of colorectal cancer in patients with ulcerative colitis.
PubMedID- 23446340 The risk of colorectal cancer in patients with long-standing ulcerative colitis or colonic crohn's disease is increased.
PubMedID- 23207933 The role of chemoprevention of colorectal cancer with 5-aminosalicylates in ulcerative colitis.
PubMedID- 23459532 Surgical treatment of colorectal cancer associated with ulcerative colitis.
PubMedID- 21793125 Background: ulcerative colitis (uc) is associated with colorectal cancer.
PubMedID- 21089179 The risk of colorectal cancer is increased in patients with long-standing ulcerative colitis.
PubMedID- 20656250 The incidence of colorectal cancer associated with ulcerative colitis (uc) increases with time.

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