eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | ulcerative colitis |
| Symptom | C0007113|rectal cancer |
| Sentences | 38 |
| PubMedID- 21793125 | Background: ulcerative colitis (uc) is associated with colorectal cancer. |
| PubMedID- 25649787 | Despite a low overall risk of colorectal cancer in patients with ulcerative colitis of relatively short duration, there is evidence that malignancies may be missed in that initial window. |
| PubMedID- 23459532 | Surgical treatment of colorectal cancer associated with ulcerative colitis. |
| PubMedID- 26357617 | Risk factors for developing cca in psc patients include elevated serum bilirubin, chronic ulcerative colitis with colorectal cancer or dysplasia, variceal bleeding, proctocolectomy, and polymorphisms of the natural killer group 2, member d (nkg2d) gene (encoding a protein involved in nk cell activity).78, 82, 83 the duration of psc may not be a risk factor for the development of cca, which is contrary to the risk factors of neoplasia in inflammatory bowel disease.77 it is suggested that dominant strictures, defined as a common bile duct stenosis with less than 1.5 mm diameter remaining in the common bile duct or a common hepatic duct stenosis close to the bifurcation leaving less than 1.0 mm diameter of the common hepatic duct,84, 85 may serve as primary indicators of concomitant cca.86 it is very challenging to distinguish between benign strictures from psc activity and cca as they can have similar characteristics on imaging. |
| PubMedID- 22289873 | Risk of colorectal cancer in patients with ulcerative colitis: a meta-analysis of population-based cohort studies. |
| PubMedID- 22156448 | Does colorectal cancer in ulcerative colitis patients constitute a risk for chemotherapy refractoriness. |
| PubMedID- 25347248 | Colorectal cancer in ulcerative colitis. |
| PubMedID- 21038106 | Colorectal cancer is one of the complications of ulcerative colitis (uc) and the risk of cancer increases as the duration of the disease becomes longer. |
| PubMedID- 22810474 | Conclusion: in our cohort, rectal cancer in the setting of chronic ulcerative colitis was rare, often presented at an early stage, and was not always diagnosed preoperatively. |
| PubMedID- 21873166 | Clinical course of colorectal cancer in patients with ulcerative colitis. |
| PubMedID- 22610004 | Challenges in calculating the risk for colorectal cancer in patients with ulcerative colitis. |
| PubMedID- 22292619 | The risk of colorectal cancer in ulcerative colitis patients is estimated to be as high as 40%. |
| PubMedID- 20698214 | Clinicopathological study of colorectal cancer occurring in patients with ulcerative colitis: results from a single hospital in japan. |
| PubMedID- 25888857 | Avoiding restorative proctocolectomy for colorectal cancer in patients with ulcerative colitis based on preoperative diagnosis involving p53 immunostaining: report of a case. |
| PubMedID- 20656250 | The incidence of colorectal cancer associated with ulcerative colitis (uc) increases with time. |
| PubMedID- 25823771 | It has been more than 40 years since the colonoscopic surveillance program for colorectal cancer (crc) in patients with long-standing ulcerative colitis (uc) was introduced (1). |
| PubMedID- 21425209 | Myeloperoxidase immunohistochemistry as a measure of disease activity in ulcerative colitis: association with ulcerative colitis-colorectal cancer, tumor necrosis factor polymorphism and runx3 methylation. |
| PubMedID- 21404516 | Colorectal cancer, in patients with ulcerative colitis, is detected in the resected tissue of approximately 5% of patients, according to the literature. |
| PubMedID- 19906011 | The development of colorectal cancer in ulcerative colitis is a function of disease duration, with the risk approaching 14% at 25 years. |
| PubMedID- 24262637 | Cost-effectiveness analysis of chromoendoscopy for colorectal cancer surveillance in patients with ulcerative colitis. |
| PubMedID- 25834332 | Aim: to determine the incidence and risk factors for colorectal cancer (crc) in patients with ulcerative colitis from a low prevalence region for crc. |
| PubMedID- 21466491 | How to manage the risk of colorectal cancer in ulcerative colitis. |
| PubMedID- 23435402 | Five-year mortality in colorectal cancer patients with ulcerative colitis or crohn's disease: a nationwide population-based cohort study. |
| PubMedID- 21618350 | Background: chronic ulcerative colitis (uc) is associated with an increased colorectal cancer risk which may be secondary to repetitive mucosal injury. |
| PubMedID- 25981516 | Psc is a premalignant condition, associated with higher rates of hepatobiliary and colorectal cancer in patients with ulcerative colitis (uc). |
| PubMedID- 24766737 | The pathogenesis of colorectal cancer in patients with ulcerative colitis is triggered by inflammation-dependent mechanisms 4. |
| PubMedID- 21089179 | The risk of colorectal cancer is increased in patients with long-standing ulcerative colitis. |
| PubMedID- 25797989 | Surveillance colonoscopy (sc) is considered important for the early detection and treatment of colorectal cancer (crc) in patients with ulcerative colitis (uc). |
| PubMedID- 25280558 | The risk of colorectal cancer in patients with ulcerative colitis. |
| PubMedID- 23867875 | Methylated eyes absent 4 (eya4) gene promotor in non-neoplastic mucosa of ulcerative colitis patients with colorectal cancer: evidence for a field effect. |
| PubMedID- 23446340 | The risk of colorectal cancer in patients with long-standing ulcerative colitis or colonic crohn's disease is increased. |
| PubMedID- 21647200 | Although progress has been made in the understanding of inflammation-driven carcinogenesis, markers based on these findings possess insufficient sensitivity or specificity to be usable as reliable biomarkers for risk of colorectal cancer development in patients with ulcerative colitis. |
| PubMedID- 24295648 | Unique endoscopic findings of colitis-associated colorectal cancer in a patient with ulcerative colitis and lynch syndrome. |
| PubMedID- 21040676 | Development of colorectal cancer in ulcerative colitis. |
| PubMedID- 23207933 | The role of chemoprevention of colorectal cancer with 5-aminosalicylates in ulcerative colitis. |
| PubMedID- 25605985 | Copy number variations are progressively associated with the pathogenesis of colorectal cancer in ulcerative colitis. |
| PubMedID- 22552273 | Dysplasia and colorectal cancer in a patient with ulcerative colitis and primary sclerosing cholangitis: a case report and a short review of the literature. |
| PubMedID- 23139655 | Surgical procedure for sporadic colorectal cancer in patients with mild ulcerative colitis. |
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