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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease thymoma
Symptom C0086438|hypogammaglobulinemia
Sentences 3
PubMedID- 25860215 Good syndrome (gs) is characterized as thymoma complicated with hypogammaglobulinemia and involves various immunodeficient conditions including depleted b cells, reduced t cells, and inversion of the cd4/cd8 ratio.4 it was first described by dr. robert good in 1954.5 although the pathogenesis of gs is still uncertain, a bone marrow defect impairing b-cell maturation has been suggested.
PubMedID- 22073609 thymoma with hypogammaglobulinemia is called good syndrome.
PubMedID- 20175853 Good's syndrome (hypogammaglobulinemia with thymoma) presenting intractable opportunistic infections and hyperkeratotic lichen planus.

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