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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease thrombocytopenia
Symptom C0085669|acute leukemia
Sentences 3
PubMedID- 23038974 Aim: to study the deposition of donor platelets (dp) in myelosuppressive thrombocytopenia (tp) in patients with acute leukemia (al) or lymphosarcoma (lsa), by using a radionuclide label (51cr) for dp.
PubMedID- 25861635 In thrombocytopenia associated with acute leukemia, low tpo levels are presumably caused by the presence of tpo receptor on myeloid leukemic cells.
PubMedID- 21534873 Tkis are generally well tolerated, but they can induce platelet dysfunction, which is of particular concern in the setting of thrombocytopenia in patients with acute leukemia.

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