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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease thrombocytopenia
Symptom C0034150|purpura
Sentences 8
PubMedID- 25884311 Conclusion: when thrombocytopenia rapidly develops in patients with idiopathic thrombocytopenic purpura immediately following pregnancy, the possibility of a thrombogenic state and differential diagnosis, including antiphospholipid syndrome and collagen vascular disease, should be considered.
PubMedID- 26400844 For example, eltrombopag (promacta, glaxosmithkline, london, uk), originally approved using orphan drug designation in 2008 for the treatment of thrombocytopenia in patients with immune thrombocytopenic purpura, was later approved for thrombocytopenia in patients with hepatitis c, a non-rare condition.
PubMedID- 24987409 Five days later, she developed a syndrome that was characteristic of thrombotic thrombocytopenic purpura with fever, thrombocytopenia, microangiopathic hemolysis, renal impairment and neurological dysfunction in the form of confusion and coma.
PubMedID- 22493563 It is highly desirable that life threatening conditions like thrombotic thrombocytopenic purpura and other causes of thrombocytopenia should be excluded.
PubMedID- 21853665 Thus, the patients were diagnosed as immune thrombocytopenic purpura due to the isolated thrombocytopenia, large platelets on blood and bone marrow smears and increased megakaryocytes in the bone marrow.
PubMedID- 23720092 Introduction: bleeding risk because of thrombocytopenia in patients with thrombotic thrombocytopenic purpura (ttp) often causes concern during placement of the central venous catheter for plasma exchange.
PubMedID- 23738162 Thrombotic thrombocytopenic purpura (ttp) consists of the pentad of thrombocytopenia, hemolytic anemia, fever, neurologic abnormalities, and renal disease.
PubMedID- 24033710 Our patient, a 26-year-old man, had attacks of thrombotic thrombocytopenic purpura (ttp) with thrombocytopenia and a urine dipstick positive for hemoglobin (4+), often as the only sign of hemolytic activity.

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