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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease thrombocytopenia
Symptom C0024530|malaria
Sentences 15
PubMedID- 22866922 P. falciparum malaria is associated with thrombocytopenia in pregnant women in this setting.
PubMedID- 23777034 Resurgence of complicated malaria associated with severe thrombocytopenia in a tertiary care hospital in delhi.
PubMedID- 23888081 This is not surprising because thrombocytopenia is associated with cerebral malaria , and in fact children in this study had lower levels of platelets.
PubMedID- 25604366 thrombocytopenia in malaria: can platelet counts differentiate malaria from other infections.
PubMedID- 25285308 Nevertheless, thrombocytopenia in malaria is observed to improve with disease resolution, and a normal platelet count is usually reported within 7 days after the initiation of antimalarial treatment .
PubMedID- 24490093 Unusual presentation of vivax malaria with anaemia, thrombocytopenia, jaundice, renal disturbance, and melena: a report from malang, a nonendemic area in indonesia.
PubMedID- 23350022 The pathogenesis of thrombocytopenia in malaria have been suggested due to peripheral destruction, splenic pooling or consumption coagulopathy but de mast et al have hypothesized that thrombocytopenia in early malaria is associated with gpib shedding in absence of systemic platelet activation and consumptive coagulopathy.25 malaria is considered to show seasonal variation in india with maximum prevalence in rainy season from july to november.7 the study also showed that positive predictive value of thrombocytopenia for the malaria infection increased during the months of july to october when maximum number of cases were reported in the laboratory while it decreased during the other months and thus the role of thrombocytopenia as predictor for malaria is retained and shows increase when the incidence of malaria increases.
PubMedID- 24572501 The mechanisms that produce thrombocytopenia in malaria are not known but seem related to a greater severity of illness (25).
PubMedID- 21687657 These features are not consistent with thrombocytopenia in malaria, especially in acute uncomplicated knowlesi malaria where thrombocytopenia is a characteristic.
PubMedID- 25928218 thrombocytopenia is commonly associated with malaria in hiv- populations and our data is consistent with a recent study that also reported normal platelet counts in hiv co-infected subjects .
PubMedID- 22289302 A study investigating the relationship that parasite density has on platelet count showed that malaria-infected children with thrombocytopenia (decreased platelet count) were younger, had higher parasitaemia, lower hemoglobin levels, an increased mean platelet volume, and exhibited platelet aggregation .
PubMedID- 24324686 thrombocytopenia in malaria is reported to be a consequence of anti-body induced platelet destruction, coagulopathy and platelet adhesion to the activated endothelium .
PubMedID- 24327084 Conclusions: vivax malaria is associated with transient thrombocytopenia which does not lead to significant bleeding in children.
PubMedID- 22811952 Fifty-three percent of patients with malaria showing thrombocytopenia in our study is close to others reporting low platelets as 57% .
PubMedID- 21073022 Platelet transfusions are not required for malaria patients with thrombocytopenia who have no bleeding.

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