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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease thalassemia
Symptom C0024530|malaria
Sentences 2
PubMedID- 25915902 In a conclusion, a high frequency of alleles such as g6pd deficiency, hbs, hbc and α-thalassemia associated with malaria resistance were present on bioko island.
PubMedID- 22133230 Recent studies in kenya and ghana have shown that individuals who inherit two malaria-protective genetic disorders of haemoglobin-alpha(+) thalassaemia and sickle cell trait-experience a much lower level of malaria protection than those who inherit sickle cell trait alone.

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