eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | systemic scleroderma |
| Symptom | C0919725|digital necrosis |
| Sentences | 2 |
| PubMedID- 20040651 | Antineutrophil cytoplasmic antibody-positive digital necrosis in a patient with limited systemic sclerosis. |
| PubMedID- 21478179 | The incidence of digital necrosis during chemotherapy in patients with systemic sclerosis is unknown, and the mechanism by which it occurs is unclear, but the three reports published to date, including the present case, suggest that physicians should be very cautious about administering gemcitabine-based chemotherapy to patients with systemic sclerosis. |
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