eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | systemic scleroderma |
| Symptom | C0410000|overlap syndrome |
| Sentences | 3 |
| PubMedID- 25885224 | Most anti-pm/scl antibodies recognize two components, pm/scl-100 and pm/scl-75 , and are found mostly in patients with overlap syndrome (ol) of pm and systemic scleroderma (ssc) (approximately 25%) , as well as in pm or ssc patients (3% to 13%) ; however, they are rarely found in other diseases, such as sjögren’s syndrome (ss) . |
| PubMedID- 21886637 | Patients with the overlap syndrome of dermatomyositis and systemic sclerosis may have a specific antinuclear antibody, the anti-pm/scl, directed against a nucleolar-protein complex. |
| PubMedID- 20819768 | Mctd is an overlap syndrome with features of systemic sclerosis, sle, polymyositis and positive anti-u1rnp antibodies. |
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