eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | systemic scleroderma |
| Symptom | C0034069|pulmonary fibrosis |
| Sentences | 13 |
| PubMedID- 21107283 | pulmonary fibrosis in systemic sclerosis: association with myocardial fibrosis. |
| PubMedID- 21637368 | Percentage volumes of calgranulin b proved significantly higher in bal of ipf patients than sarcoidosis patients or patients with pulmonary fibrosis associated with systemic sclerosis or controls (figure 1) . |
| PubMedID- 26099251 | Ultrasound signs of pulmonary fibrosis in systemic sclerosis as timely indicators for chest computed tomography. |
| PubMedID- 23949623 | To investigate the utility of an open-source digital imaging and communication in medicine viewer software-osirix-to assess pulmonary fibrosis (pf) in patients with systemic sclerosis (ssc). |
| PubMedID- 25849157 | pulmonary fibrosis, idiopathic, in patients with systemic sclerosis or post-radiation or chemotherapy, is a major cause of death and its treatment is considered a major unmet need 2. |
| PubMedID- 20425529 | Pathogenesis of pulmonary fibrosis in systemic sclerosis: lessons from interstitial lung disease. |
| PubMedID- 25505696 | Ger disease (gerd) has been associated with ipf and with pulmonary fibrosis in patients with systemic sclerosis (scleroderma), and ger with aspiration may play a role in triggering and/or driving lung inflammation and fibrosis in ipf and scleroderma, and it has been linked to acute exacerbations in patients with ipf . |
| PubMedID- 20156945 | Elevated serum concentrations of triggering receptor expressed on myeloid cells-1 in diffuse cutaneous systemic sclerosis: association with severity of pulmonary fibrosis. |
| PubMedID- 19844733 | Autoantibody against one of the antioxidant repair enzymes, methionine sulfoxide reductase a, in systemic sclerosis: association with pulmonary fibrosis and vascular damage. |
| PubMedID- 26444860 | In a study using lung tissues from systemic sclerosis patients with pulmonary fibrosis and pulmonary hypertension, hsu et al. |
| PubMedID- 22096366 | In wound healing, they differentiate into myofibroblasts, yet remain able to present antigen to lymphocytes.31 in animal models of lung fibrosis, circulating fibrocytes are recruited to injured lungs as an integral component of the pathogenesis of pulmonary fibrosis.32 in patients with systemic sclerosis, there are more fibrocytes in the circulation, expressing higher levels of il-10 upon proinflammatory stimulation compared with healthy individuals.33 the concept of fibrocytes being involved in ild is appealing because these cells are derived from an inexhaustible source, the bone marrow, and thus can replenish fibrotic effector cells in the tissue. |
| PubMedID- 21239758 | Objective: to clarify the clinical significance of concentrations of serum clara cell 16-kda protein (cc16; previously denoted cc10) in the diagnosis and monitoring of pulmonary fibrosis (pf) in patients with systemic sclerosis (ssc); and to compare cc16 levels with levels of the current most reliable serum markers for pf, such as krebs von den lungen-6 (kl-6) antigen and surfactant protein-d (sp-d). |
| PubMedID- 23894628 | Previous studies reported the association of serum parc with active pulmonary fibrosis in patients with systemic sclerosis , and increased plasma level has been observed in childhood acute lymphoblastic leukemia and gaucher disease 1. |
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