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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease small cell carcinoma
Symptom C0686377|central nervous system metastases
Sentences 3
PubMedID- 20740181 We report for the first time a case of non-small cell lung cancer with central nervous system metastases harboring a rare egfr double activating mutation who showed a good clinical response to erlotinib, regardless of his poor performance status, as swallowing is not possible.
PubMedID- 21030498 Development of central nervous system metastases in patients with advanced non-small cell lung cancer and somatic egfr mutations treated with gefitinib or erlotinib.
PubMedID- 24765300 Past medical history included non-small cell lung cancer with recurrent central nervous system metastases for which he was receiving whole brain radiation and temozolomide.

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