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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease small cell carcinoma
Symptom C0220650|brain metastases
Sentences 44
PubMedID- 20009927 Multimodality management of non-small cell lung cancer patients with brain metastases.
PubMedID- 25565443 brain metastases in patients with alk+ non-small cell lung cancer: clinical symptoms, treatment patterns and economic burden.
PubMedID- 26359696 Objective: we used brain radiotherapy as a surrogate for the presence of brain metastases in patients with non-small cell lung cancer (nsclc) to determine the prevalence of brain metastases using the surveillance epidemiology and end results database.
PubMedID- 21792167 Combined treatment of non-small cell lung cancer with synchronous brain metastases: a single center experience.
PubMedID- 26218580 Background: numerous studies have focused on the treatment of non-small cell lung cancer patients with brain metastases.
PubMedID- 22933980 Outcome of small cell lung cancer (sclc) patients with brain metastases in a routine clinical setting.
PubMedID- 25583566 Egfr tyrosine kinase inhibitors versus cranial radiation therapy for egfr mutant non-small cell lung cancer with brain metastases: a systematic review and meta-analysis.
PubMedID- 26520640 We prospectively addressed whether egfr and kras mutations, eml4-alk, ros1 and ret rearrangements, or wild-type (wt), affects radiosurgery outcomes and overall survival (os) in non-small cell lung cancer (nsclc) patients with brain metastases (bm).
PubMedID- 23958057 High plasma fibrinogen concentration and platelet count unfavorably impact survival in non-small cell lung cancer patients with brain metastases.
PubMedID- 21924038 The aim of this study is to explore prognostic factors in non-small cell lung cancer (nsclc) in patients with brain metastases diagnosed by constrast-enhanced mri after whole brain radiotherapy.
PubMedID- 24197981 Egfr mutation status and its impact on survival of chinese non-small cell lung cancer patients with brain metastases.
PubMedID- 21972711 The role of surgical treatment of primary non-small cell lung cancer with synchronous brain metastases.
PubMedID- 22613338 Background and objective: the aim of this study is to evaluate the efficacy of selected arterial infusion chemotherapy in treating non-small cell lung cancer (nsclc) with multiple brain metastases and corresponding factors to influencing prognosis.
PubMedID- 25208818 The aim of this study was to explore prognostic factors for non-small cell lung cancer (nsclc) patients with brain metastases (bm) on the basis of egfr mutation status.
PubMedID- 24577133 Background: survival upon diagnosis of brain metastases (bm) in patients with non-small cell lung cancer (nsclc) is highly variable and established prognostic scores do not include tissue-based parameters.
PubMedID- 22613339 Progress of treatments in non-small cell lung cancer with brain metastases.
PubMedID- 24904894 Outcome of surgical resection of symptomatic cerebral lesions in non-small cell lung cancer patients with multiple brain metastases.
PubMedID- 25628027 Squamous cell histology was associated with worse prognosis after resection of brain metastases in patients with non-small cell lung cancer.
PubMedID- 22335887 Although the presence of epidermal growth factor receptor (egfr) mutation and good response to gefitinib have been reported in non-small cell lung cancer (nsclc) patients with miliary brain metastases, the influence of the egfr mutations on the radiographic features remains unclear.
PubMedID- 26275366 Delayed leukoencephalopathy of non-small cell lung cancer patients with brain metastases underwent whole brain radiation therapy.
PubMedID- 23021771 Miliary brain metastases in 2 cases with advanced non-small cell lung cancer harboring egfr mutation during gefitinib treatment.
PubMedID- 22818215 A 69 year old lady has an extensive small cell lung cancer with newly diagnosed brain metastases.
PubMedID- 20395118 The management of brain metastases in patients with non-small cell lung cancer-is it time to go back to the drawing board.
PubMedID- 23518381 Screening for brain metastases in patients with stage iii non-small cell lung cancer: is there additive value of magnetic resonance imaging above a contrast-enhanced computed tomography of the brain.
PubMedID- 25347291 Whole brain radiotherapy plus concurrent chemotherapy in non-small cell lung cancer patients with brain metastases: a meta-analysis.
PubMedID- 24606446 Background: the incidence of brain metastases (bm) varies in patients with non-small cell lung cancer (nsclc), calls into question the value of prophylactic cranial irradiation (pci).
PubMedID- 23189011 Sekine et al,3 evaluated the correlation between non-small cell lung cancer patients with brain metastases and epidermal growth factor receptor (egfr) mutations on molecular studies, as well as the radiological findings.
PubMedID- 24256883 Survival and treatment options are limited for patients with brain metastases arising from non-small cell lung cancer (nsclc).
PubMedID- 25842091 Treatment and control of brain metastases are important in patients with non-small cell lung cancer (nsclc).
PubMedID- 25031274 Background: median survival of non-small cell lung cancer (nsclc) patients with brain metastases is poor.
PubMedID- 23392751 Chemotherapy for small cell lung cancer with brain metastases.
PubMedID- 20591632 Aims: to study various prognostic factors affecting outcome and to validate radiation therapy oncology group recursive partitioning analysis (rpa) class in non-small cell lung cancer (nsclc) with brain metastases treated with short-course accelerated radiotherapy (scar).
PubMedID- 20728237 Cisplatin, fotemustine and whole-brain radiotherapy in non-small cell lung cancer patients with asymptomatic brain metastases: a multicenter phase ii study of the gruppo oncologico italia meridionale (goim 2603).
PubMedID- 23376611 Bevacizumab is now allowed for non-small cell lung cancer (nsclc) patients with brain metastases and non-squamous histology.
PubMedID- 24725335 Purpose: we intended to identify risk factors that affect brain metastases (bm) in patients with locally advanced non-small cell lung cancer (la-nsclc) receiving definitive radiation therapy, which may guide the choice of selective prevention strategies.
PubMedID- 22678505 A 74-year-old diabetic patient who had a history of non-small cell lung cancer with brain metastases and subsequent treatment with srs, presented with a focal lesion in the left centrum semiovale with progressively worsening edema.
PubMedID- 22461932 Past medical history was notable for small cell lung cancer (sclc) with brain metastases.
PubMedID- 21574647 Using a unique study set of 42 brain metastases from patients with breast or nonsmall cell lung cancer (nsclc), the phosphorylation/activation states of 128 key signaling proteins involved in cancer signaling were measured in laser capture microdissected tumor epithelium using reverse phase protein microarray (rpma) technology.
PubMedID- 20658721 Gamma knife radiosurgery in non small cell lung cancer patients with brain metastases: treatment results and prognostic factors.
PubMedID- 21317753 High-dose erlotinib for refractory brain metastases in a patient with relapsed non-small cell lung cancer.
PubMedID- 25925626 Another trial84 examined the use of primary chemotherapy for newly diagnosed non-small cell lung cancer with synchronous brain metastases (with delayed wbrt at brain relapse) versus wbrt administered first.
PubMedID- 24310312 The outcome of bifocal surgical resection in non-small cell lung cancer with synchronous brain metastases: results of a single center retrospective study.
PubMedID- 21697413 Conclusion: radiobiological models suggest that if there is a non-uniform distribution of microscopic brain metastases in patients with small cell lung cancer, higher population-based metastasis-free rates might be achievable with non-uniform irradiation compared with the same integral whole-brain dose delivered as a uniform prescription.
PubMedID- 26310285 Herein, we conducted a self-controlled study to evaluate the effect of wbrt on the permeability of bbb in non-small cell lung cancer (nsclc) patients with brain metastases (bm).

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