eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | shigellosis |
| Symptom | C0009450|infection |
| Sentences | 43 |
| PubMedID- 25171098 | 3%; aor-4.93 (95% ci-3.19-7.63), had higher co-infection with shigella 3% vs. |
| PubMedID- 22932645 | In a recent study, we demonstrated that infection with shigella and salmonella triggered an early state of intracellular amino acid (aa) starvation causing mtor dissociation from endomembranes, downregulation of mtor activity and activation of the eif2ak4/gcn2-eif2s1/eif2alpha/atf3 signaling axis. |
| PubMedID- 22019906 | infection of macrophages with salmonella typhimurium, shigella flexneri, legionella pneumophila, and pseudomonas aeruginosa all induce il-1β secretion via activation of an nlrc4 inflammasome. |
| PubMedID- 24416363 | Our results indicate that infection of enterocytes with wild-type shigella induces molecular changes in occludin, leading to its disengagement from the tight junction complex that, together with the associated disruption of claudin-1 and zo-1 organization, contribute to increase paracellular permeability to macromolecules. |
| PubMedID- 24851099 | infection with invasive shigella species results in intestinal inflammation in humans but no symptoms in adult mice. |
| PubMedID- 24137160 | It is noteworthy that starvation-induced autophagy also contributes to host defense in the event of infection with shigella or salmonella species (118). |
| PubMedID- 24079544 | Interestingly, while infection with listeria, shigella, neisseria and salmonella reduced ter substantially over time, infection with the c. jejuni inv+/trans+ strains 81–176, f38011 und nctc11168 did not influence ter significantly . |
| PubMedID- 24877110 | It is established that infection with shigella can lead to the syndrome of bloody or watery diarrhea; nonetheless, studies, when the information of bloody diarrhea is reported by patients the frequencies, are divergent . |
| PubMedID- 25133066 | Gastrointestinal or genitourinary infections with salmonella, shigella, campylobacter, yersinia, and chlamydia trachomatis may cause inflammatory oligoarticular or polyarticular sterile arthritis, usually starting within four weeks of infection . |
| PubMedID- 23727423 | We have previously demonstrated the capacity of outer membrane vesicles (omvs) to protect mice against an experimental infection with shigella flexneri. |
| PubMedID- 23228631 | For instance, studies have successfully assessed symptomselicited by an experimental infection with rhinoviruses(76–78), shigella(79), respiratory syncytial virus(80) or enterotoxigenic escherichia coli(81). |
| PubMedID- 24516390 | Immunoblotting analysis revealed that infection with wt shigella or salmonella induces prominent asc dimer formation in wt, but not asc-deficient macrophages (figure 5a, upper panel). |
| PubMedID- 26379246 | infection with shigella is accompanied by strong genotoxic stress and cellular damage . |
| PubMedID- 23738211 | Reactive arthritisthis has been observed after enteric infection with shigella, salmonella, yersinia, and campylobacter and genital infection with neisseria gonorrhea. |
| PubMedID- 21368893 | Thus, we can envision a scenario characterized by the simultaneous activation of apoptotic and anti-apoptotic pathways, whose balance is finely modulated during infection with shigella toward the eventual commitment to death of the infected cell. |
| PubMedID- 24432507 | Simultaneous infection with shigella sonnei and vibrio cholerae in a young child. |
| PubMedID- 25944982 | However, prolonged infection with shigella is accompanied by the production of ptdlns5p, a lipid mediator, to close the connexin hemichannels . |
| PubMedID- 21077843 | P62 was also found to be situated at the crossroads of several signalling pathways during infection with shigella, a bacterium that replicates in the cytoplasm. |
| PubMedID- 22606962 | It is an acute intestinal infection caused by bacteria of the genus shigella, with a minimum infective dose as low as 10–100 bacterial cells. |
| PubMedID- 23960189 | For example, by virtue of its ecology, the gut is susceptible to infection with salmonella and shigella, organisms which are not pathogens in the skin. |
| PubMedID- 22675469 | As a test system, we assessed the inflammatory response elicited by infection of rabbits with shigella flexneri. |
| PubMedID- 25514820 | Little is known, however, about the burden of infection and disease due to shigella spp. |
| PubMedID- 21654922 | Figure 2 shows that the seasonal distribution of infection with shigella spp. |
| PubMedID- 24736407 | shigellosis (bacillary dysentery), the result of infection with shigella, is an enteric infectious disease responsible for approximately 1,100,000 deaths per year worldwide 1. |
| PubMedID- 21673991 | Since shigellosis is often associated with secondary respiratory infections , , , we further investigated cathelicidin expression in lung and trachea during shigella infection as well as the remote systemic effect of oral treatment with pb and nab. |
| PubMedID- 20429941 | infection with shigella causes an intense acute inflammatory reaction that leads to the destruction of the colonic epithelium 1. |
| PubMedID- 22467150 | Bacteremia and intrauterine infection with shigella sonnei in a pregnant woman with aids. |
| PubMedID- 25887696 | infection with shigella was also strongly associated with having more than 10 stools on the most severe day of illness (table 3).table 2clinical symptoms in children with gastroenteritis, by presence of enteropathogensa>10 stools/day n/total (%)vomiting n/total (%)fever >39°c n/total (%)dec positive single infection4/14 (28.6%)13/16 (81.3%)9/15 (60.0%)dec positive mixed infection6/22 (27.3%)18/22 (81.8%)12/21 (57.1%)dec negative23/121 (19.0%)113/131 (86.3%)78/128 (60.9%)dec and rotavirus positive6/21 (28.6%)19/21 (90.5%)11/20 (55.5%)dec negative and rotavirus positive14/68 (20.6%)65/72 (90.3%)40/71 (56.3%)dec positive and rotavirus negative5/18 (27.8%)15/20 (75.0%)12/19 (63.2%)dec and rotavirus negative14/64 (21.9%)59/71 (83.1%)40/68 (58.8%)eaec positive8/16 (50%)*13/18 (72.2%)**6/17 (35.3%)*eaec negative32/162 (19.8%)151/173 (87.3%)102/167 (61.1%)eaec and rotavirus positive5/9 (55.6%)*8/9 (88.9%)*2/9 (22.2%)eaec negative and rotavirus positive15/80 (18.8%)76/84 (90.5%)49/82 (59.8%)eaec positive and rotavirus negative3/7 (42.9%)5/9 (55.6%)4/8 (50.0%)eaec and rotavirus negative16/75 (21.3%)69/82 (84.1%)48/79 (60.8%)atypical epec positive3/19 (15.8%)17/19 (85.5%)14/18 (77.8%)**atypical epec negative37/159 (23.3%)147/172 (85.5%)94/166 (56.6%)atypical epec and rotavirus positive1/10 (10.0%)9/10 (90.0%)8/9 (88.9%)atypical epec negative & rotavirus positive19/79 (24.1%)75/86 (90.4%)43/82 (52.4%)atypical epec positive & rotavirus negative2/9 (22.2%)8/9 (88.9%)6/9 (66.7%)atypical epec and rotavirus negative17/73 (23.3%)66/82 (80.5%)46/78 (59.0%)*pv <0.05 **pv <0.1.athis analysis in based on the total number of children with complete information on the various clinical symptoms, and detection of enteric pathogens. |
| PubMedID- 21470448 | And co-infection with rotavirus and shigella spp. |
| PubMedID- 23724523 | Purpose of investigation: this report describes a case of urinary tract infection (uti) due to shigella sonnei during pregnancy. |
| PubMedID- 24332032 | Upon infection with shigella flexneri, epithelial cells release atp through connexin hemichannels. |
| PubMedID- 23583496 | infection with shigella spp. |
| PubMedID- 25722880 | Nod1 not only activates nf-κb, but also mapk jnk as seen in infection with shigella flexneri . |
| PubMedID- 24130485 | Taken together, these results strongly suggest that mait cells are specifically activated during the course of an enteric bacterial infection with a shigella dysenteriae strain in human. |
| PubMedID- 25848798 | infection with wild-type shigella (m90t) caused a large increase in pml nbs in many of the infected cells (fig 1a). |
| PubMedID- 23874731 | infection with shigella spp. |
| PubMedID- 24137567 | In a very recent study, it was demonstrated that infection with shigella and salmonella triggered an early state of intracellular amino acid starvation causing the dissociation of mtor from endomembranes and the downregulation of its activity (tattoli et al., 2012). |
| PubMedID- 23817334 | In multivariate analysis, malnutrition (odds ratio ), age of the child (24-59 months; 1.67 ), fever (1.65 ), abdominal pain (1.87 ), straining (5.93 ), and infection with shigella (3.26 ) and vibrio cholerae (2.21 ) were shown to be significantly associated with msd. |
| PubMedID- 23691156 | Conclusions: both severe intestinal disease and extra-intestinal manifestations of shigellosis occur with infection by any of the four species of shigella, but are most common with s. |
| PubMedID- 22768099 | Cortactin tyrosine phosphorylation is dependent on the pathogen: it occurs upon infection with shigella, vaccinia virus and cryptosporidium–, whereas cortactin phosphorylation is not necessary for uptake of epec and ehec . |
| PubMedID- 24750584 | From january 2012 through april 2013, infection with 4 shigella spp. |
| PubMedID- 22624016 | Furthermore, unlike infection with salmonella or shigella, the gall bladder was rarely colonized with b. pseudomallei, , . |
| PubMedID- 21151550 | Prior association of hus resulting from preceding infection with veracytotoxin or shigella-like toxin-producing bacteria, in particular the enteric pathogen enterohemorrhagic escherichia coli (ehec) o157:h7 and other e. coli serotypes have been documented.1–3 ehec results in hemorrhagic bloody diarrhea. |
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