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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease sheehan syndrome
Symptom C0242343|panhypopituitarism
Sentences 3
PubMedID- 22138080 Objectives: to indicate cardiogenic shock as a very rare but serious clinical consequence of untreated panhypopituitarism attributable to sheehan syndrome; to emphasize the importance of eliciting a detailed endocrine and obstetric history in women presenting with idiopathic heart failure; to highlight the diagnostic shortcomings of screening for thyroid dysfunction solely with thyroid-stimulating hormone determinations; and to report the reversibility of severe heart failure induced by long-term pituitary insufficiency.
PubMedID- PMC2994176 The patient did not have subclinical hypothyroidism (where we expect a normal t4 and mild elevation of tsh); in fact, she had severe secondary hypothyroidism as a part of panhypopituitarism because of sheehan syndrome.
PubMedID- 21424753 sheehan's syndrome presents with panhypopituitarism after childbirth, usually preceded by post partum hemorrhage.

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