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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease schistosomiasis
Symptom C0239946|hepatic fibrosis
Sentences 4
PubMedID- 22291593 Extensive hepatic fibrosis is associated with hepatosplenic schistosomiasis, a form of the disease that occurs at a frequency of 5 – 10% in untreated infected populations and which has a high mortality rate .
PubMedID- 25965781 The increase in timp1 observed at the latest time point mirrors the clinical situation where elevated levels are associated with hepatic fibrosis due to schistosomiasis japonica in supernatents of patient pbmcs (peripheral blood mononuclear cells) stimulated with schistosome egg antigen .
PubMedID- 21145322 We conclude that ast and apri levels were reliable and sensitive markers for differentiating significant hepatic fibrosis in patients with advanced schistosomiasis japonica.
PubMedID- 23684910 Schistosoma japonicum scfv-il18 fusion dna ameliorates hepatic fibrosis in schistosomiasis-infected mice via improving local concentration of il-18 in liver.

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