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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease sarcoidosis
Symptom C0702166|acnes
Sentences 6
PubMedID- 24351617 acnes associated with sarcoidosis were searched.overall odds ratios (or) and 95% confidence intervals (ci) were obtained.
PubMedID- 22596102 Thus, p. granulosum is more likely than m. tuberculosis to be the cause of sarcoidosis in patients without p. acnes detected within granulomas by the pab antibody.
PubMedID- 24053623 The disease association of p. granulosum is less clear, though it has been found in a few cases of endocarditis and endophthalmitis, and has been associated, like p. acnes, with sarcoidosis .
PubMedID- 26204953 Immune response to propionibacterium acnes in patients with sarcoidosis--in vivo and in vitro.
PubMedID- 24455697 The review proposes mechanisms of granuloma formation in response to p. acnes in subjects with sarcoidosis and introduces a new concept of endogenous infection caused by hypersensitivity to indigenous bacteria.
PubMedID- 24366580 Although a number of prior studies have demonstrated the consistent presence of bacterial dna (mostly atypical mycobacteria and propionibacterium acnes) in sarcoidosis tissue, the current study is the first to correlate clinical outcomes with the presence of detectable bacterial dna, suggesting the most promising candidates for treatment.

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