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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease psoriasis
Symptom C0037284|skin lesion
Sentences 12
PubMedID- 20800455 Abnormal dna methylation in skin lesions and pbmcs of patients with psoriasis vulgaris.
PubMedID- 24566842 Because most patients will be treated first for the skin lesions associated with psoriasis, dermatologists are in a unique position to screen for and diagnose early psa .
PubMedID- 20943046 The role of etanercept on the expression of markers of t helper 17 cells and their precursors in skin lesions of patients with psoriasis vulgaris.
PubMedID- 26474319 Importantly, s. aureus is detected in about 50% of skin lesions in patients with psoriasis , and is associated with a higher pasi score .
PubMedID- 24727542 Increased chemerin levels are found in the skin lesions of lupus and acute psoriasis and in the kidneys of patients with severe lupus nephritis, which is associated with the tissue infiltration of pdcs, suggesting that chemerin may play a pro-inflammatory role in autoimmune diseases, possibly by mediating pdc chemotaxis.1,6,7 however, several studies have also demonstrated that the administration of exogenous chemerin exerts potential anti-inflammatory activities in experimental peritonitis and acute lung injury.8,9 in addition, several synthetic peptides derived from the c-terminal domain of human or mouse pro-chemerin were reported to display significant bioactivity.8,10,11 for example, the chemerin15 (c15) peptide was shown to ameliorate zymosan-induced peritonitis, which could be due to its capacity to enhance macrophage phagocytosis of microbial particles and apoptotic cells.8,11 however, another study failed to detect any activity of the c15 peptide.9 it is still unknown whether these peptides are generated in vivo due to the lack of a detection assay.
PubMedID- 22063458 The relationship between quality of life (qol) and skin lesion improvement due to psoriasis treatment has been recently underlined.
PubMedID- 22528235 Expression of irf-4 and ibp in skin lesions of patients with psoriasis vulgaris.
PubMedID- 24003271 The skin lesions of the patients with psoriasis were assessed by the same dermatologist.
PubMedID- 23090423 Because of the development of hyperkeratotic skin lesions consistent with guttate psoriasis, the infliximab treatment was discontinued.
PubMedID- 23518141 Cd4(+) t-cell/mast-cell conjugates in skin lesions from patients with psoriasis were analyzed by using 3-color immunohistochemistry and confocal microscopy.
PubMedID- 23369618 Whole-genome dna methylation in skin lesions from patients with psoriasis vulgaris.
PubMedID- 20333526 Expression of th1 and th2 cytokine-associated transcription factors, t-bet and gata-3, in peripheral blood mononuclear cells and skin lesions of patients with psoriasis vulgaris.

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