eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | psoriasis |
| Symptom | C0033774|pruritus |
| Sentences | 13 |
| PubMedID- 26005355 | In the epidermis of psoriasis patients with pruritus, the expression of κ-opioid receptor and dynorphin a was significantly decreased compared with in healthy controls.59 therefore, a κ-opioid system in the psoriatic epidermis plays some role in the regulation of itching. |
| PubMedID- 22648457 | The presented suggest we should not underestimate pruritus in psoriasis and must consider this symptom in planning therapy. |
| PubMedID- 20599294 | Improvements in pruritus scores correlated with improvements in psoriasis area and severity index after 8 weeks of etanercept therapy in two phase iii trials. |
| PubMedID- 20028449 | psoriasis was significantly associated with pruritus (p = 0.0001), pachyonychia (p = 0.00001), palmoplantar keratoderma (p = 0.0001) and hypereosinophilia (p = 0.008). |
| PubMedID- 24756248 | Impact of functional pruritus compared with mild psoriasis on quality of life: a cross-sectional questionnaire study in turkey. |
| PubMedID- 25384221 | Assessment of pruritus in patients with psoriasis and atopic dermatitis: subjective and objective tools. |
| PubMedID- 26415584 | Despite the high frequency of pruritus in psoriasis, to date there is no single antipruritic therapy dedicated specifically to treat itch in this disease. |
| PubMedID- 24716586 | The itch severity score (iss), a 0-10 numeric rating scale, was used to assess pruritus due to psoriasis in a phase 2 b trial of tofacitinib, a novel oral janus kinase inhibitor. |
| PubMedID- 25473225 | Results: sixty-four patients (80%) complained of pruritus associated with scalp psoriasis, which negatively affected their quality of life to varying degrees. |
| PubMedID- 25376448 | Objective: the objective of this study was to examine pruritus and qol in patients with moderate-to-severe psoriasis treated with etanercept (etn) in the pristine clinical trial. |
| PubMedID- 24901012 | This mechanism may contribute to the pruritus, reported in patients with psoriasis table 1(c) . |
| PubMedID- 23285231 | In addition, the majority of patients experience pain and pruritus associated with their psoriasis on a regular basis. |
| PubMedID- 24438964 | pruritus severity in patients with psoriasis is not correlated with psoriasis disease severity. |
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