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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease psoriasis
Symptom C0011570|depression
Sentences 22
PubMedID- 25781210 Irs per 1000 patient-years of af were 3.21, 5.02, 8.41, 5.39 and 7.41; and irs of stroke were 2.62, 3.09, 6.71, 3.62 and 9.03 for the reference population, mild psoriasis without depression, mild psoriasis with depression, severe psoriasis without depression and severe psoriasis with depression, respectively.
PubMedID- 26550011 Exacerbation of psoriasis with worsening depression and anxiety is common, and a variety of physiological pathways may be involved in mediating this relationship.
PubMedID- 24459298 although the potential contributors of depression in psoriasis are numerous, they mostly evolve from poor quality of life and may include increased rates of pruritus, social stigmatization, joint manifestation and poor treatment compliance all of which have been associated with depression in previous studies.
PubMedID- 20015170 Multivariate models controlling for age, gender and consulting behaviour indicated that psoriasis is independently associated with depression (or 1.49; 95% ci 1.20-1.86), stress-related disorders (or 1.41; 95% ci 1.22-1.62), behaviour disorders (or 1.58; 95% ci 1.05-2.39), diabetes (or 1.21 95% ci 1.04-1.40), hypertension (or 1.34; 95% ci 1.18-1.51), dyslipidaemia (or 1.29; 95% ci 1.07-1.55), and obesity (or 1.63; 95% ci 1.39-1.90).
PubMedID- 26421371 Conclusions and relevance: self-reported history of psoriasis was independently associated with major depression as assessed by a validated screening tool, even when controlling for comorbidities.
PubMedID- 22216042 In a cross-sectional study by magin et al.33 it was found that 'non-psychiatric diagnosis' psychological morbidity-embarrassment, shame, self-consciousness, impairments of self-image, self-confidence and self-esteem, anger, and stigmatization-were more prominent than symptoms of anxiety and depression in patients with acne, psoriasis and atopic dermatitis.
PubMedID- 24082881 In addition to its cutaneous manifestations, psoriasis has been associated with inflammatory arthritis, depression, anger, anxiety, frustration, and considerable health-related quality of life impairment, which appear independent of objective disease severity .
PubMedID- 22844272 's study showed that the magnitude of anxiety and depression in patients with psoriasis is higher than that in healthy individuals, but they found no association between severities of psoriasis with anxiety , whereas harvima et al.
PubMedID- 26086213 This study examined the risk of new-onset depression in patients with psoriasis in a nationwide danish cohort including some 5 million people in the period 2001-2011.
PubMedID- 24372845 The hazard ratio for depression in psoriasis patients vs. the general population is about 1.4–1.5 and increases with severity of psoriasis.20,21 depression is reported in 15–62% of patients (table 1),21,22 and suicidal ideation is reported in 5.5% to 9.7% of psoriasis patients.23 other psychiatric diagnoses are also common.19 psychiatric symptoms are associated with reduced quality of life in psoriasis patients.24,25 alcohol abuse is reported in 15–30% of psoriasis patients.26–29 there is little evidence for an association between alcohol consumption and severity of psoriasis, but excess alcohol consumption appears to be associated with depression in psoriasis patients,26,28 and may adversely affect treatment outcomes, particularly regarding poor compliance.28 psoriasis patients have an increased likelihood of smoking compared with the general population, with odds ratios from 1.31 to 2.96 reported.30–32 smoking is also associated with psoriasis disease severity,29,32 and is correlated with impaired psoriasis-related quality of life.33 all of these addictive behaviours may be related to the emotional burden of the psoriasis patient having a stigmatising disease.
PubMedID- 26186277 Objectives: in this prospective cohort study, we investigated the risk of incident depression among individuals with psoriasis and psoriatic arthritis (psa).
PubMedID- 26280176 psoriasis is associated with depression, myocardial infarction (mi) and stroke.
PubMedID- 25520742 The aim of this study was to examine the prevalence of alexithymia and its association with anxiety and depression in patients with psoriasis compared with healthy participants, while taking into consideration demographic and clinical variables.
PubMedID- 25184912 The prevalence of depression in psoriasis patients is about20%, and it is believed that depression onset can increase the risk for cardiovasculardisease.36 in our study, theprevalence of depression was 25.8%, but it was not related to the severity or extent ofthe skin condition.
PubMedID- 25672294 Evidence shows an association of psoriasis with arthritis, depression, inflammatory bowel disease and cardiovascular diseases.
PubMedID- 24934916 Suicide and depression in a patient with psoriasis receiving adalimumab: the role of the dermatologist.
PubMedID- 25556559 Early onset psoriasis is associated with depression, social discrimination, and greater lt dlqi.
PubMedID- 24284419 The reported prevalence of depression in psoriasis varies substantially.
PubMedID- 23374943 When adjusting for age, bmi, gender, and depression, those with psoriasis were not more likely to experience poor sleep quality (p=0.25), nor to score in a higher insomnia category (p=0.20) or be more "sleepy" (p=0.53).
PubMedID- 25856968 The prevalence of depression in patients with psoriasis is estimated between 10 % and 62 % according to different studies.
PubMedID- 24318414 The prevalence of depression in psoriasis is estimated to be up to 30% .
PubMedID- 24003268 Kurd et al.24 reported that the adjusted hazard ratio for receiving a diagnosis of depression in patients with psoriasis, when compared with the respective control population, was 1.31 (95% confidence interval, 1.37~1.41).

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