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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease pre-eclampsia
Symptom C0036572|seizures
Sentences 8
PubMedID- 24680906 The effects of superoxide dismutase mimetic mntmpyp on the altered blood-brain barrier integrity in experimental preeclampsia with or without seizures in rats.
PubMedID- 21547090 There is significant evidence which supports the use of magnesium sulphate to prevent seizures in women with severe preeclampsia and eclampsia .
PubMedID- 21189878 For instance, severe preeclampsia could lead to eclamptic seizures and cerebral haemorrhage.
PubMedID- 24825164 Being a key drug to prevent seizures in situations of severe preeclampsia, we can make the inference that its use on the study population was almost always delayed or inappropriate, as all the included cases had seizures , .
PubMedID- 25907222 Mgso4 is a major therapy for the prevention of seizures in preeclampsia but it has been suggested to also have anti-inflammatory and vasodilatory properties.
PubMedID- 23346385 This drug reduces the risk of seizures in patients with severe preeclampsia .
PubMedID- 26126779 Cerebrovascular dysfunction during preeclampsia can lead to cerebral edema, seizures, stroke, and potentially maternal mortality.
PubMedID- 23963425 The american college of obstetricians and gynecologists and the society for maternal-fetal medicine continue to support the short-term (usually less than 48 hours) use of magnesium sulfate in obstetric care for appropriate conditions and for appropriate durations of treatment, which includes the prevention and treatment of seizures in women with preeclampsia or eclampsia, fetal neuroprotection before anticipated early preterm (less than 32 weeks of gestation) delivery, and short-term prolongation of pregnancy (up to 48 hours) to allow for the administration of antenatal corticosteroids in pregnant women between 24 weeks of gestation and 34 weeks of gestation who are at risk of preterm delivery within 7 days.

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