eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | periodontitis |
| Symptom | C0017574|gingivitis |
| Sentences | 9 |
| PubMedID- 25624628 | the expression of tlr9 is significantly upregulated in periodontitis lesions compared with gingivitis lesions. |
| PubMedID- 21584253 | gingivitis can lead to periodontitis, a condition in which gingival and bone tissues are destroyed. |
| PubMedID- 21550586 | Results: gene expression of crp is significantly elevated in periodontitis lesions compared with gingivitis lesions. |
| PubMedID- 23967169 | In susceptible individuals persistent gingivitis may lead to chronic periodontitis 1, which causes irreversible destruction of periodontal tissue. |
| PubMedID- 22845916 | Conclusions: the study shows a significant association between periodontitis (but not with gingivitis) and adverse pregnancy outcomes. |
| PubMedID- 25210259 | As the severity of inflammation increases, there is a significant increase in the crp levels as indicated by higher crp levels in periodontitis compared with gingivitis suggesting that there is a direct relationship between crp levels in gcf and periodontal destruction. |
| PubMedID- 26390822 | gingivitis affects the majority of people, and advanced periodontitis is estimated to affect 5-15% of adults. |
| PubMedID- 23046680 | gingivitis may lead to periodontitis without proper treatment; the inflammatory periodontal tissues will progress increasingly with age and may lead to pathological destruction of the tooth supporting tissues, tooth loosening and potential tooth loss . |
| PubMedID- 24632674 | Once the homeostasis of microbial diversity within the plaque is lost, gingivitis leads to periodontitis . |
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