eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | pancytopenia |
| Symptom | C0015625|fanconi anemia |
| Sentences | 7 |
| PubMedID- 24019220 | Oxandrolone for the treatment of bone marrow failure in fanconi anemia. |
| PubMedID- 20661450 | bone marrow failure in children with fanconi anemia is attributed to excessive apoptosis and subsequent failure of the hematopoietic stem cell compartment (reviewed in ). |
| PubMedID- 22683204 | bone marrow failure in fanconi anemia is triggered by an exacerbated p53/p21 dna damage response that impairs hematopoietic stem and progenitor cells. |
| PubMedID- 22178060 | Treatment of the bone marrow failure in fanconi anemia patients with danazol. |
| PubMedID- 23547077 | Purpose: allogeneic hematopoietic cell transplantation (hct) can cure bone marrow failure in patients with fanconi anemia (fa). |
| PubMedID- 24960628 | Hematopoietic cell transplantation (hct) can cure bone marrow failure in patients with fanconi anemia (fa), and it is generally accepted that these patients should receive low-intensity conditioning because of the underlying dna repair defect in their cells. |
| PubMedID- 25534205 | bone marrow failure in fanconi anemia (fa) has been linked in part to overproduction of inflammatory cytokines, to which fa stem and progenitor cells are hypersensitive. |
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