Disease | osteomalacia |
Symptom | C0235394|wasting |
Sentences | 1 |
PubMedID- 20593414 | (15) however, its important role in phosphate homeostasis became apparent only when gain-of-function mutations in fgf23 were shown to cause autosomal dominant hypophosphatemic rickets (adhr)(8) and when fgf-23, independently isolated from tumors that cause hypophosphatemia and consequently osteomalacia owing to renal phosphate wasting tumor-induced osteomalacia (tio), was shown to increase renal phosphate excretion. |
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