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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease neutropenia
Symptom C0027947|neutropenia
Sentences 6
PubMedID- 24833969 Other abnormal findings were thrombocytopenia, anemia, and leukopenia withmarked neutropenia but with normal lymphocytic and monocytic series.
PubMedID- 23623830 The most common grade 3/4 adverse events (aes) were neutropenia (14.6% of patients), followed by leukopenia, fatigue, metabolic, and gastrointestinal, with 66% showing any grade 3/4 toxicity.
PubMedID- 20564112 Three patients discontinued treatment due to persistent grade 4 (based on national cancer institute common terminology criteria for adverse events version 3.0) neutropenia with grade 3 leukopenia (2 patients) or grade 4 pulmonary embolism (1 patient).
PubMedID- 21827519 Laboratory abnormalities included leukopenia with neutropenia and lymphopenia, rouleaux formation, marked hyperproteinemia with hyperglobulinemia and normoalbuminemia, hypercalcemia, markedly increased serum urea concentration, mildly increased creatinine concentration, and proteinuria.
PubMedID- 20361278 Hemogram revealed mild leukopenia with severe neutropenia (absolute neutrophil count 256/mm(3)), normal hemoglobin and mild thrombocytopenia (115000/mm(3)).
PubMedID- 22699824 The most common grade 3/4 drug-related aes overall were neutropenia (36.0% of study population), leukopenia (27.9%) and thrombocytopenia (8.1%).

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