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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease neonatal lupus
Symptom C0018794|heart block
Sentences 2
PubMedID- 23910804 Complete congenital heart block (cchb) accompanied with neonatal lupus erythematosus is caused by an immune reaction between maternal anti-ro/ssa antibodies and the fetal heart and is generally considered an irreversible process.
PubMedID- 25545844 While current strategies are able to achieve live births in 85-90% of pregnancies, certain aspects such as prevention of preterm birth, treatment of congenital heart block due to neonatal lupus and recurrent pregnancy loss despite best management, remains challenging.

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