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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease narcolepsy
Symptom C0694563|excessive daytime sleepiness
Sentences 8
PubMedID- 24833927 Armodafinil is the pharmacologically active r-enantiomer of modafinil, a widely prescribed wake-promoting agent used to treat several sleep-related disorders including excessive daytime sleepiness associated with narcolepsy, shift work sleep disorder, and obstructive sleep apnea/hypopnea syndrome.
PubMedID- 26474479 Nonetheless, the enhancement of histamine transmission obtained by antagonism of h3 inhibitory histamine auto-receptors limits the excessive daytime sleepiness associated with narcolepsy .
PubMedID- 22550980 This article gives an overview of sodium oxybate, which has been us fda approved for the treatment of cataplexy and excessive daytime sleepiness in patients with narcolepsy, and ema approved for the treatment of narcolepsy-cataplexy.
PubMedID- 23723550 Modafinil is a stimulant drug approved for the treatment of excessive daytime sleepiness associated with narcolepsy, shift-work sleep disorder, and obstructive sleep apnea syndrome by the us food and drug administration (fda).
PubMedID- 22596015 Approximately 6 months later, narcolepsy-cataplexy with excessive daytime sleepiness occurred.
PubMedID- 22640618 Modafinil is a wake-promoting drug used for the treatment of excessive daytime sleepiness due to narcolepsy as well as excessive sleepiness associated with obstructive sleep apnea and shift work disorder.
PubMedID- 23470841 narcolepsy is a cause of excessive daytime sleepiness (eds) distinguished by abnormal intrusions of rapid eye movement (rem) sleep such as cataplexy, sleep paralysis, and hypnagogic hallucinations during wakefulness 1.
PubMedID- 20705253 The purpose of this study was to compare the objective multiple sleep latency test (mslt) and the subjective epworth sleepiness scale (ess) for evaluating the efficacy of modafinil in treating excessive daytime sleepiness in patients with narcolepsy in taiwan.

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