eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | myositis |
| Symptom | C0410000|overlap syndrome |
| Sentences | 5 |
| PubMedID- 24600322 | In the first case, the patient was definitively diagnosed with undifferentiated overlap syndrome with features of polyarthritis, myositis, and scleroderma (dactylitis), possibly induced or exacerbated by adalimumab, and in the second patient a clear diagnosis of dm (with positive anti-dna-ds and jo-1 antibodies) with some features of seronegative polyarthritis (negative rf and anti-ccp antibodies) was made. |
| PubMedID- 24389298 | In a subgroup of patients classified as overlap syndrome with myositis and ck elevation (44/325), we determined the frequency of gender distribution (70.5% women, 29.5% men), as well as clinical features; 59.1% had oesophageal involvement, 38.6% of patients had lung fibrosis, and 34.1% suffered from cardiac involvement, while less than 15.0% had kidney failure or signs for ph. |
| PubMedID- 24765389 | myositis associated with overlap syndromes is usually of paroxysmal variety and has been associated with one or another of connective tissue disorders systemic sclerosis (ssc), rheumatoid arthritis (ra), sjögren's syndrome or systemic lupus erythematous (sle). |
| PubMedID- 25883715 | overlap syndromes of sle with myositis, including dermatomyositis and polymyositis, are recognized clinically . |
| PubMedID- 24797170 | Contrary to the case of other overlap syndromes associated with myositis-specific antibodies, such as antisynthetases, we did not observe clear extramuscular involvement in anti-hmgcr+ patients. |
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