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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease myositis
Symptom C0004093|weakness
Sentences 7
PubMedID- 21457520 The idiopathic inflammatory myopathies (iims) poly-myositis (pm) and dermatomyositis (dm) are heterogeneous conditions that are historically diagnosed by proximal muscle weakness, evidence of muscle inflammation or necrosis, and characteristic skin lesions .
PubMedID- 25798107 However, among the 27 differentially methylated genes several hox genes (hoxc11, hoxd3 and hoxd4) and the developmental transcription factor wt1 were found hypomethylated in juvenile dm samples, as well as in other types of idiopathic inflammatory myopathies (iims) with muscle weakness, such as juvenile polymyositis (wang et al., 2012).
PubMedID- 22955479 Dermatomyositis is a rare autoimmune inflammatory myopathy with proximal muscle weakness and skin affection.
PubMedID- 19906360 Known as idiopathic inflammatory myopathies (iim), they all share the presence of considerable weakness due to muscle inflammation and necrosis.
PubMedID- 24648807 Dermatomyositis (dm) is an idiopathic inflammatory myopathy with progressive, symmetrical weakness of the proximal muscles and characteristic cutaneous manifestations such as poikiloderma 1.
PubMedID- 21470434 Moreover, when inflammatory myopathies present with a significant weakness at diagnosis, they carry an unfavorable impact on prognosis.
PubMedID- 26417430 Inflammatory myopathies are a group of diseases that involve chronic muscle inflammation (myositis) accompanied with muscle weakness .

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