eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | myelofibrosis |
| Symptom | C0001815|myelofibrosis |
| Sentences | 7 |
| PubMedID- 21870730 | Myeloid metaplasia with myelofibrosis associated with acute coronary syndrome. |
| PubMedID- 24880208 | Essential thrombocytosis (et) falls under the umbrella of myeloproliferative disorders, which also includes chronic myelogenous leukemia, polycythemia vera, and myelofibrosis with myeloid metaplasia. |
| PubMedID- 22282696 | Increase in fibrosis is due to liberation of cytokines such as tgf-β and pdgf from dysplastic megakaryocytes.15 the differential diagnosis includes myelofibrosis with myeloid metaplasia, chronic myelocytic leukemia and acute megakaryocytic leukemia. |
| PubMedID- 20359349 | Clonal dysregulation linked to myeloproliferative neoplasms (mpn) arising from acquired mutations in the haematopoietic progenitor cells lead to a wide range of clonal haematological malignant diseases including polycythemia vera (pv), essential thrombocythemia (et), myeloid metaplasia with myelofibrosis (mmm), chronic myelomonocytic leukemia (cmml), chronic myelogenous leukemia (cml), hypereosinophilic syndrome (hes), and systemic mast cell disease (smcd)1. |
| PubMedID- 22548075 | Most of the reported pulmonary extramedullary hematopoiesis is seen in myelofibrosis with myeloid metaplasia, a subgroup of chronic myeloproliferative disorders. |
| PubMedID- 20615740 | Objective: lenalidomide (ldm) is an immunomodulatory and anti-angiogenic drug which has been shown to be effective in several haematological disorders (multiple myeloma mm, myeloid metaplasia with myelofibrosis mf and myelodysplastic syndrome mds). |
| PubMedID- 23259545 | myelofibrosis with myeloid metaplasia (mmm) is a rare malignant hematological disease of the hematopoietic stem cells with a median age at diagnosis of 60 years. |
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