eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | muscular dystrophy |
| Symptom | C0234958|muscle degeneration |
| Sentences | 3 |
| PubMedID- 23707352 | We have investigated the immune-modulating effect of one of such drugs, molsidomine, able to slow the progression of muscular dystrophy in the alpha-sarcoglican-null mice, a model for the limb girdle muscular dystrophy 2d, sharing several hallmarks of muscle degeneration with other muscular dystrophies. |
| PubMedID- 24312627 | Here we set out to identify the contribution of canonical apoptotic pathways to skeletal muscle degeneration in muscular dystrophy by genetically deleting a known inhibitor of apoptosis, apoptosis repressor with a card domain (arc), in dystrophic mouse models. |
| PubMedID- 22239878 | muscle degeneration in muscular dystrophies often includes a period of edema before fatty replacement of muscle tissue. |
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