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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease multiple system atrophy
Symptom C0497327|dementia
Sentences 6
PubMedID- 24753321 Based on a comprehensive evidence-based review, the authors propose future avenues of research that ultimately may lead to diagnostic criteria for cognitive impairment and dementia associated with multiple system atrophy.
PubMedID- 22037599 Alpha-synuclein in the cerebrospinal fluid differentiates synucleinopathies (parkinson disease, dementia with lewy bodies, multiple system atrophy) from alzheimer disease.
PubMedID- 22424094 Cother clinical diagnoses included alzheimer disease, parkinson's disease, corticobasal degeneration, multiple system atrophy, parkinson's disease with dementia, vascular dementia, progressive non-fluent aphasia and dementia.
PubMedID- 26452984 In most-but not all-studies published to date total csf alpha-syn concentrations have been found to be decreased in disorders related to alpha-syn pathology, i.e., pd, dementia with lewy-bodies and multiple system atrophy.
PubMedID- 26096603 However, it is uncertain whether nr4a3 is also involved in diseases such as dementia with lewy bodies, multiple system atrophy, and other neurodegenerative disorders such as tauopathies, tdp-43 proteinopathies and polyglutamine diseases.
PubMedID- 26501269 Atypical parkinsonism syndromes, such as dementia with lewy bodies, multiple system atrophy, progressive supranuclear palsy and corticobasal degeneration, are neurodegenerative diseases with complex clinical and pathological features.

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