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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease multiple myeloma
Symptom C1136085|monoclonal gammopathy
Sentences 7
PubMedID- 21113108 multiple myeloma with iga-monoclonal gammopathy was diagnosed by serum and urine electrophoresis including immunodetection with an anti-dog iga antibody and bone marrow aspirations.
PubMedID- 22142681 Can whole-body low-dose multidetector ct exclude the presence of myeloma bone disease in patients with monoclonal gammopathy of undetermined significance (mgus).
PubMedID- 22826793 The patient was diagnosed as having non-secretory ige myeloma with igg monoclonal gammopathy of undetermined significance (mgus) based on the following findings: i) serum immunoelectropheresis identified a monoclonal igg and κ protein; ii), atypical plasma cells made up 55.5% of the nucleated cells on bone marrow aspirate; iii) immunohistochemical staining showed most plasma cells were positive for ige and κ, but a few for igg; iv) there was no increase in serum ige level; v) serum immunofixation did not show any ige monoclonal band.
PubMedID- 20461463 monoclonal gammopathy associated with multiple myeloma and visceral leishmaniasis in the dog: a comparison of two cases.
PubMedID- 24363850 Any patient presenting with cardiomyopathy with preserved systolic function, heavy albuminuria, an unexplained sensorimotor peripheral neuropathy, hepatomegaly, or atypical monoclonal gammopathy of undetermined significance or myeloma should be suspected of having al amyloidosis 5.
PubMedID- 26448754 Various hematologic malignancies such as monoclonal gammopathy of undetermined significance, multiple myeloma and waldenström's macroglobulinemia as well as solid cancers such as bladder cancer feature cells with aberrant splice variants of has1, which are associated with cancer diagnosis, relapse and poor outcome (reviewed in ).
PubMedID- 23285429 Aim: to detect and quantify monoclonal gammopathy in suspected cases of multiple myeloma and to differentiate them from benign conditions, because of the vast difference between their prognosis and management.

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