eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | multiple myeloma |
| Symptom | C0035078|renal failure |
| Sentences | 37 |
| PubMedID- 25285800 | Efficacy, toxicity and mortality of autologous sct in multiple myeloma patients with dialysis-dependent renal failure. |
| PubMedID- 22260636 | Evaluation of multiple myeloma patients presenting with renal failure in a university hospital in the year 2010. |
| PubMedID- 24877060 | In a trial performed in myeloma patients presenting with renal failure, patients were randomized to receive either sodium bicarbonate to render their urine neutral or no supplement. |
| PubMedID- 19693498 | Acute renal failure in patients with multiple myeloma (mm) requiring dialysis is a serious complication and is associated with extremely poor survival. |
| PubMedID- 25816886 | Conclusion: our meta-analysis results showed that plasmapheresis used as an adjunct to chemotherapy had a benefit in the management of dialysisdependent multiple myeloma patients with renal failure. |
| PubMedID- 23591252 | Cast nephropathy is one of the major causes of renal failure in patients with multiple myeloma resulting from precipitation of free light chains inside the tubules. |
| PubMedID- 22022183 | A study showed that the development of dialysis-dependent renal failure in patients with myeloma can be reversed by hsct after high levels of chemotherapy (29). |
| PubMedID- 23249872 | In this article, we report the case of a 63-year-old man who presented with severe acute renal failure due to myeloma cast nephropathy and whose kidney function improved significantly following treatment with dexamethasone and a course of 8 plasma exchanges. |
| PubMedID- 21188171 | There were two grade 4 renal failures in patients with multiple myeloma (mm). |
| PubMedID- 20835325 | Complete remission of lambda light chain myeloma presenting with acute renal failure following treatment with bortezomib and steroids. |
| PubMedID- 22920640 | The primary cause of renal failure in myeloma is damage to the kidney by excessive amounts of light chain produced by the myeloma tumor, giving rise to cast nephropathy (myeloma kidney), although there are several other important precipitants. |
| PubMedID- 26390728 | Dialysis-dependent renal failure in patients with multiple myeloma: reversibility factors. |
| PubMedID- 25018923 | Aminoglycoside-associated severe renal failure in patients with multiple myeloma treated with thalidomide. |
| PubMedID- 21368487 | In this study, we retrospectively analyzed the 8 myeloma patients with renal failure who have received bortezomib in our hospital.one patient had already required constant hemodialysis before bortezomib.bortezomib treatment was performed for 229 days, during which time it was injected 30 times.the other 2 patients with chronic renal failure also showed no further renal impairment due to bortezomib.in the remaining 5 patients, serum creatinine levels decreased through 2 cycles(total: 8 injection)of bortezomib treatment.two patients were complicated with herpes zoster, and 2 patients were complicated with neuropathy in grade 3.we showed the safety and efficacy of bortezomib in japanese patients with multiple myeloma complicated with renal failure.we should positively consider the therapeutic choice of bortezomib for the refractory myeloma with renal failure. |
| PubMedID- 26124916 | Immunoglobulin d multiple myeloma with rapidly progressing renal failure. |
| PubMedID- 21511832 | Myeloma kidney is the major cause of severe irreversible renal failure in patients with multiple myeloma. |
| PubMedID- 23597473 | Clinical study of bortezomib in the treatment of multiple myeloma patients with renal failure. |
| PubMedID- 21264915 | High-dose glucocorticoids improve renal failure reversibility in patients with newly diagnosed multiple myeloma. |
| PubMedID- 25329484 | Aim of this review is to provide an overview of treatments of multiple myeloma patients with acute renal failure coming from most recent clinical trials. |
| PubMedID- 23712232 | Effectiveness of haemodiafiltration with ultrafiltrate regeneration in renal failure due to multiple myeloma. |
| PubMedID- 21175542 | Aggressive removal of circulating free light chains (flc) by blood purification accompanied by chemotherapy is a promising approach for the treatment of acute renal failure due to myeloma cast nephropathy. |
| PubMedID- 20955270 | Our systematic review does not suggest a benefit of plasmapheresis independent of chemotherapy for multiple myeloma patients with acute renal failure in terms of overall survival, recovery from dialysis, or improvement in renal function. |
| PubMedID- 24895606 | Early articles linked iv administration of contrast agents with the development of renal failure in patients with multiple myeloma, leading to the conclusion that iv contrast media are contraindicated in patients with myeloma because they are at a high risk for developing cin . |
| PubMedID- 25671952 | Conclusions: iss stage and renal failure due to multiple myeloma at presentation have a significant impact on survival. |
| PubMedID- 22889516 | Use of continuous venovenous hemofiltration for acute renal failure due to multiple myeloma cast nephropathy. |
| PubMedID- 23705905 | Current treatments for renal failure due to multiple myeloma. |
| PubMedID- 21339749 | renal failure in multiple myeloma: a medical emergency. |
| PubMedID- 20689322 | Background: the presence of renal failure in patients with multiple myeloma (mm) has been considered an ominous prognostic factor associated with a significantly decreased life expectancy. |
| PubMedID- 26154652 | The cases include non-adherent patients who discontinued their immunosuppressive medications, transplantation between identical twins, kidney transplantation after a successful bone marrow graft from the same donor and simultaneous bone marrow and kidney transplantation for the treatment of multiple myeloma with associated renal failure. |
| PubMedID- 24385726 | Among patients diagnosed as myeloma, 25% present with acute renal failure (arf) . |
| PubMedID- 25089594 | Bortezomib improves outcome after sct in multiple myeloma patients with end-stage renal failure. |
| PubMedID- 21358693 | Plerixafor for pbsc mobilisation in myeloma patients with advanced renal failure: safety and efficacy data in a series of 21 patients from europe and the usa. |
| PubMedID- 23350020 | Approximately 10% of these patients will either be dialysis-dependent or require dialysis.9 patients with multiple myeloma associated with renal failure generally have a worse prognosis due to a more aggressive disease and a reduced quality of life caused by increased complications.1,14 therefore, it is especially important in myeloma patients to find methods to reduce flc levels in the body. |
| PubMedID- 21515102 | New insights in the treatment of myeloma with renal failure. |
| PubMedID- 23656195 | Down-regulation of microrna-29c is associated with renal failure in multiple myeloma. |
| PubMedID- 22041268 | And one patient had myeloma cast nephropathy with acute renal failure. |
| PubMedID- 26022018 | renal failure in patients with multiple myeloma. |
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