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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease multiple myeloma
Symptom C0021079|immunosuppression
Sentences 3
PubMedID- 25984103 A previous case has been reported, but it was a case of early onset after non-myeloablative haematopoietic stem cell transplantation for myeloma with subsequent strong immunosuppression due to a severe graft-versus-host disease 3.
PubMedID- 22481961 However, it is unknown to what extent and for how long the passively transferred humoral immunity compensates the severe disease- and therapy-related immunosuppression in myeloma patients.
PubMedID- 22421410 Human lymphocyte antigen-g (hla-g) is an immunosuppressive molecule that induces functional silencing of immune component cells and can be responsible for immunosuppression in patients with multiple myeloma (mm).

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