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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease metabolic syndrome x
Symptom C0020473|hyperlipidemia
Sentences 13
PubMedID- 23700549 Patients having both type 2 diabetes mellitus and hypertension often have obesity and hyperlipidemia, which are features of the metabolic syndrome.
PubMedID- 24900991 Among these risk factors, type 2 diabetes, hypertension, and hyperlipidemia are components of metabolic syndrome.
PubMedID- 22292039 In addition, elevated plasma ffa is a risk factor for metabolic syndrome, which can lead to hyperlipidemia, fatty liver and insulin resistance .
PubMedID- 25918936 Dyslipidemia, abnormal endogenous lipid metabolism (including hyperlipidemia), is associated with metabolic syndrome.
PubMedID- 22162948 On the other hand, tlr5-deficient mice exhibit hyperphagia and develop hallmark features of metabolic syndrome, including hyperlipidemia, hypertension, insulin resistance, and increased adiposity , and these alterations are the consequence of alterations in the gut microbiota.
PubMedID- 20961464 Mutant mice homozygous for clock exibit an altered diurnal feeding rhythm, developing metabolic syndrome with hyperlipidemia , and a reduced amount of time spent asleep both in entrained and free-running conditions .
PubMedID- 25672777 metabolic syndrome (mets) is associated with abdominal obesity, hyperlipidemia, insulin resistance, and type 2 diabetes mellitus, and increases the risk of cardiovascular disease.
PubMedID- 20480025 Prolonged hyperglycemia and hyperlipidemia, typically within development of metabolic syndrome, leads to the dysfunction of the pancreatic β-cells, reflected in autocrine insulin resistance, impaired insulin secretion, decreased expression of genes involved in insulin production and finally decrease in β-cell mass caused by apoptosis.
PubMedID- 25646773 Nafld refers to a spectrum of hepatic disorders secondary to an increase in hepatic triglyceride (tg) content in the setting of the metabolic syndrome that is associated with obesity, hypertension, hyperlipidemia and type ii diabetes 2.
PubMedID- 25912321 Shr-cp/cp rats developed progressive kidneyfailure, exacerbated by hyperlipidemia with metabolic syndrome.
PubMedID- 21760736 This metabolic syndrome model with hyperlipidemia and insulin resistance was established (along with nonalcoholic fatty liver) in hamsters fed a high-fat, high-cholesterol, inadequate methionine- and choline-containing diet.
PubMedID- 20920192 In the wake of current prevalence rates of hyperlipidemia amongst people with metabolic syndrome ffn can serve as efficacious adjuncts to pharmo-therapy during all stages of treatment.
PubMedID- 26377420 Obesity and hyperlipidemia among other components of the metabolic syndrome are known risk factors for prostate cancer .

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