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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease metabolic syndrome x
Symptom C0020459|hyperinsulinemia
Sentences 17
PubMedID- 21699736 Insulin resistance and hyperinsulinemia are characteristic features of the metabolic syndrome.
PubMedID- 22087859 Obesity displays characteristics of a metabolic syndrome, with hyperinsulinemia and resistance to insulin, leading to type ii diabetes, atherosclerosis, hypertension, hepatic steatosis, and sometimes cancer 1.
PubMedID- 23981814 In most of the cases, we have women affected by metabolic syndrome with hyperinsulinemia or insulin resistance but not classical diabetes, and the use of metformin is not allowed for this group of patients.
PubMedID- 22967456 Indeed, over nutrition during lactation provokes obesity and hyperinsulinemia, among other hallmarks of metabolic syndrome, whereas under nutrition permanently decreases body weight and causes metabolic changes.
PubMedID- 22383969 Overnutrition during lactation provokes obesity and hyperinsulinemia, among other hallmarks of the metabolic syndrome, whereas undernutrition permanently decreases body weight and insulin levels.
PubMedID- 20923961 Generalized impairment of vasodilator reactivity during hyperinsulinemia in patients with obesity-related metabolic syndrome.
PubMedID- 21575958 hyperinsulinemia in patients with metabolic syndrome or insulin resistance may be a key factor in this phenomenon.
PubMedID- 22566722 Some authors have suggested that val therapy in wwe induces hyperandrogenism and a metabolic syndrome with centripetal obesity, hyperinsulinemia, lipid abnormities and polycystic appearing ovaries and that, therefore, val treatment in young women is relatively contraindicated9.
PubMedID- 25097586 Regarding insulin resistance, our results were in accordance with previous studies which suggested that insulin resistance or hyperinsulinemia is associated with metabolic syndrome , enhanced urate reabsorption and reduced urate excretion in the kidney, leading to elevated serum uric acid concentrations .
PubMedID- 25843159 Infants born in such conditions have undergone metabolic changes, such as fetal hypo- or hyperinsulinemia, which may lead to development of dysmetabolic syndrome and other chronic diseases in adulthood.
PubMedID- 25383490 Impaired fasting blood glucose is one of the landmark signs of metabolic syndrome, together with hyperinsulinemia, dyslipidemia, hypertension, and a chronic proinflammatory, pro-oxidative, and prothrombotic environment.
PubMedID- 24381427 The prevalence of non-alcoholic fatty liver disease was 15.6 % in non alcoholic population and 68.5 % of non-alcoholic fatty liver disease had metabolic syndrome, which was associated with hyperinsulinemia, insulin resistance, insulin insensitivity along with elevated levels of waist circumference, blood pressure, triglyceride, ffa and decreased hdl cholesterol.
PubMedID- 21980496 Insulin resistance and the resultant hyperinsulinemia, commonly associated with the metabolic syndrome, are involved in the imbalance of formation and utilization of free fatty acids leading to steatosis , .
PubMedID- 23363255 Conclusions: hyperinsulinemia and high prevalence of various symptoms of metabolic syndrome (ms) were found in high percentage of patients with after load precordial pain who were referred to coronarography.
PubMedID- 24520329 The aromatase knockout (arko) mice have been shown to harbor factors of metabolic syndrome with central adiposity, hyperinsulinemia and male-specific hepatic steatosis.
PubMedID- 25833158 These results support a developmental mechanism by which periconceptional hyperinsulinemia associated with maternal metabolic syndrome, obesity, and/or diabetes can act on the oocyte and affect offspring cardiovascular development, function, and congenital heart malformation.
PubMedID- 23863634 Insulin resistance (ir) and hyperinsulinemia are hallmarks of the metabolic syndrome, as are central adiposity, dyslipidemia, and a predisposition to type 2 diabetes, atherosclerotic cardiovascular disease, hypertension, and certain cancers.

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