eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | melanoma, malignant |
| Symptom | C1608408|malignant transformation |
| Sentences | 8 |
| PubMedID- 23293541 | melanoma results from malignant transformation of melanocytes. |
| PubMedID- 25289356 | A congenital melanocytic nevus depending on the size of the lesion is one of the risk factors for developing childhood melanoma because of the possible malignant transformation. |
| PubMedID- 20885933 | melanoma results from malignant transformation of melanocytes. |
| PubMedID- 24376839 | Uveal melanoma (um), which results from a malignant transformation of uveal melanocytes (located in the iris, ciliary body and choroid), is the most common intraocular malignancy in adults. |
| PubMedID- 21324102 | Both models display nevus-like melanocytic hyperplasia; however, the focus has been on the malignant transformation of these nevi to melanoma and not the nevi themselves. |
| PubMedID- 26064422 | Malignant melanoma, a neoplasm arising from malignant transformation of melanocytes, is predominantly a disease of the skin but may in rare instances occur at other sites, including the mucous membranes (hard palate, maxillary gingiva, lip, throat, esophagus, vulva, vagina, and perianal region) and the eye (uvea and retina). |
| PubMedID- 25763285 | The presence of congenital melanocytic nevi depending on the size of the lesions is one of the risk factors for developing childhood melanoma because of the possible malignant transformation 3. |
| PubMedID- 22529586 | 4 malignant transformation of melanocytes into melanoma cells produces marked changes in morphology, organization and biologic characterization of melanocytes. |
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